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一例严重的卡尔氏关节孢菌角膜真菌病病例。

A Severe Case of Arthrographis kalrae Keratomycosis.

作者信息

Ramli Siti Roszilawati, Francis Alex Lourdes, Yusof Yushaniza, Khaithir Tzar Mohd Nizam

机构信息

Institute for Medical Research, Jalan Pahang, 50588 Kuala Lumpur, Wilayah Persekutuan, Malaysia.

Pathology Department, Hospital Raja Permaisuri Bainun, Jalan Hospital, 30990 Ipoh, Perak, Malaysia.

出版信息

Case Rep Infect Dis. 2013;2013:851875. doi: 10.1155/2013/851875. Epub 2013 Nov 27.

DOI:10.1155/2013/851875
PMID:24377053
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3860077/
Abstract

A 52-year-old man with diabetes developed a unilateral central corneal ulcer after accidental foreign body inoculation. He complained of pain and loss of visual acuity in the injured eye, which displayed redness and edema and eventually discharged pus. A corneal scraping from the left eye orbit revealed fungal elements, and cultures of the material grew a fungus. The isolate was identified as Arthrographis kalrae based on gross and microscopic morphologies. The patient received amphotericin B intravenously and itraconazole orally. The wound healed following surgical intervention, but the patient lost the use of his left eye.

摘要

一名52岁的糖尿病男性在意外接种异物后发生了单侧中央角膜溃疡。他主诉受伤眼疼痛和视力丧失,该眼表现为发红和水肿,最终排出脓液。从左眼眼眶刮取的角膜组织显示有真菌成分,该材料培养出一种真菌。根据大体和微观形态,分离株被鉴定为卡尔氏节丛孢菌。患者接受了静脉注射两性霉素B和口服伊曲康唑治疗。手术干预后伤口愈合,但患者左眼失明。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3118/3860077/dbbc505eac18/CRIM.ID2013-851875.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3118/3860077/c526815829e5/CRIM.ID2013-851875.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3118/3860077/dbbc505eac18/CRIM.ID2013-851875.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3118/3860077/c526815829e5/CRIM.ID2013-851875.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3118/3860077/dbbc505eac18/CRIM.ID2013-851875.002.jpg

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2
Mycotic keratitis: epidemiology, diagnosis and management.真菌性角膜炎:流行病学、诊断与治疗。
Clin Microbiol Infect. 2013 Mar;19(3):210-20. doi: 10.1111/1469-0691.12126. Epub 2013 Feb 9.
3
A rare pulmonary infection caused by Arthrographis kalrae.由金龟子假尾孢引起的罕见肺部感染。
Arq Bras Oftalmol. 2020 Jan-Feb;83(1):65-68. doi: 10.5935/0004-2749.20200004.
4
First case of fungemia in a patient with cystic fibrosis.首例囊性纤维化患者发生真菌血症的病例。
Med Mycol Case Rep. 2016 Nov 30;14:8-11. doi: 10.1016/j.mmcr.2016.11.002. eCollection 2016 Dec.
J Med Microbiol. 2012 Apr;61(Pt 4):593-595. doi: 10.1099/jmm.0.037531-0. Epub 2011 Dec 8.
4
Severe Arthrographis kalrae keratomycosis in an immunocompetent patient.免疫功能正常患者的严重卡尔拉枝孢菌角膜炎
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5
Endocarditis caused by Arthrographis kalrae.由卡尔拉枝孢菌引起的心内膜炎。
Ann Thorac Surg. 2010 Jul;90(1):e4-5. doi: 10.1016/j.athoracsur.2010.04.021.
6
Arthrographis kalrae, a rare causal agent of onychomycosis, and its occurrence in natural and commercially available soils.卡尔拉氏 arthrogrphy,一种罕见的甲真菌病病原体,及其在自然和商业上可获得的土壤中的存在。
Med Mycol. 2010 Mar;48(2):384-9. doi: 10.3109/13693780903219014.
7
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8
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Cornea. 2004 Apr;23(3):314-7. doi: 10.1097/00003226-200404000-00018.
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