聚维酮碘灌注的玻璃体切除术治疗严重真菌性眼内炎。
Povidone iodine-infused pars plana vitrectomy for severe fungal endophthalmitis.
作者信息
Huang Denis, Tran Lillian, Li Jennifer Yh, Lee William, Kim Esther, Moussa Kareem
机构信息
Department of Ophthalmology & Vision Science, University of California, Davis, Sacramento, CA, USA.
出版信息
Am J Ophthalmol Case Rep. 2024 Oct 24;36:102207. doi: 10.1016/j.ajoc.2024.102207. eCollection 2024 Dec.
PURPOSE
Arthrographis kalrae is an opportunistic fungus that can cause a severe and atypical endophthalmitis. In limited studies, low-dose povidone iodine has been shown to be effective in treating fulminant bacterial endophthalmitis. In this case report, we describe the successful treatment of recalcitrant keratitis-associated endophthalmitis with intraocular povidone iodine during pars plana vitrectomy.
OBSERVATIONS
A patient with keratitis-associated endophthalmitis had persistent disease despite aggressive medical management. The infection resolved following pars plana vitrectomy with infusion of dilute povidone iodine. No toxicity was noted postoperatively.
CONCLUSIONS AND IMPORTANCE
Povidone iodine-infused pars plana vitrectomy offers promise as a treatment for infectious endophthalmitis that fails medical management. This is the first report demonstrating eradication of fungal endophthalmitis using povidone iodine-infused pars plana vitrectomy.
目的
卡尔氏节菱孢是一种机会性真菌，可引起严重且非典型的眼内炎。在有限的研究中，低剂量聚维酮碘已被证明对治疗暴发性细菌性眼内炎有效。在本病例报告中，我们描述了在玻璃体切割术中使用眼内聚维酮碘成功治疗顽固性角膜炎相关性眼内炎的情况。
观察结果
一名患有角膜炎相关性眼内炎的患者尽管接受了积极的药物治疗，但疾病仍持续存在。在玻璃体切割术中注入稀释的聚维酮碘后，感染得到解决。术后未观察到毒性反应。
结论与意义
注入聚维酮碘的玻璃体切割术有望成为治疗药物治疗无效的感染性眼内炎的方法。这是第一份证明使用注入聚维酮碘的玻璃体切割术根除真菌性眼内炎的报告。
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