Prpich Cassandra Y, Santamaria Alessandra C, Simcock James O, Wong Hoong Kien, Nimmo Judith S, Kuntz Charles A
Southpaws Specialty Surgery for Animals, 3 Roper St, Moorabbin, VIC 3189, Australia.
J Am Vet Med Assoc. 2014 Jan 15;244(2):187-94. doi: 10.2460/javma.244.2.187.
To determine outcomes for dogs with soft tissue sarcomas in the distal aspects of the limbs that underwent second intention healing after wide excision (2-cm lateral surgical margins and a margin 1 fascial plane deep) of the tumors.
Retrospective case series.
31 dogs with soft tissue sarcomas in the distal aspects of the limbs that underwent second intention healing following wide local excision of their tumors.
Tumors were excised with 2-cm lateral margins and a margin 1 fascial plane deep to tumors. Wounds healed by means of second intention. Time to healing, complications during healing, and information regarding tumor recurrence were recorded.
All tumors were excised with histologically tumor-free margins. Twenty-nine (93.5%) wounds healed completely by second intention (median time, 53 days). Two (6.5%) dogs required free skin graft procedures to facilitate healing. Complications during open wound management developed for 7 (22.6%) dogs. Long-term complications were detected for 8 (25.8%) dogs, including intermittent epidermal disruption (5/31 [16.1%]) and wound contracture (3/31 [9.7%]). All complications were managed conservatively. Local tumor recurrence was detected for 1 (3.2%) dog. Median follow-up time was 980 days (range, 380 to 2,356 days). No patients died because of tumor-related causes.
Results of this study indicated second intention healing of large wounds in the distal aspects of the limbs was complete and typically without complications for dogs that underwent wide excision of soft tissue sarcomas. Wide local excision of soft tissue sarcomas in the distal aspects of the limbs with 2-cm lateral margins and margins 1 fascial plane deep to the tumors provided excellent long-term local tumor control.
确定四肢远端患有软组织肉瘤的犬只在肿瘤广泛切除（手术切缘外侧2厘米且深达1个筋膜平面）后进行二期愈合的预后情况。
回顾性病例系列研究。
31只四肢远端患有软组织肉瘤且在肿瘤广泛局部切除后进行二期愈合的犬只。
肿瘤切除时，外侧切缘为2厘米，且深达肿瘤深面1个筋膜平面。伤口通过二期愈合。记录愈合时间、愈合过程中的并发症以及肿瘤复发情况。
所有肿瘤切除时组织学切缘均无肿瘤。29只（93.5%）伤口通过二期愈合完全愈合（中位时间为53天）。2只（6.5%）犬需要进行游离皮肤移植手术以促进愈合。7只（22.6%）犬在开放伤口处理过程中出现并发症。8只（25.8%）犬检测到长期并发症，包括间歇性表皮破损（5/31 [16.1%]）和伤口挛缩（3/31 [9.7%]）。所有并发症均采用保守治疗。1只（3.2%）犬检测到局部肿瘤复发。中位随访时间为980天（范围为380至2356天）。无患者因肿瘤相关原因死亡。
本研究结果表明，对于接受软组织肉瘤广泛切除的犬只，四肢远端大伤口的二期愈合是完全的，且通常无并发症。四肢远端软组织肉瘤采用外侧2厘米切缘且深达肿瘤深面1个筋膜平面的广泛局部切除可提供良好的长期局部肿瘤控制。
