• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

δ13C同位素比率质谱法在甲基苯丙胺特征分析中的应用:麻黄碱和伪麻黄碱类样品与苯基-2-丙酮类样品的比较

The use of δ13C isotope ratio mass spectrometry for methamphetamine profiling: comparison of ephedrine and pseudoephedrine-based samples to P2P-based samples.

作者信息

Toske Steven G, Morello David R, Berger Jennifer M, Vazquez Etienne R

机构信息

U.S. Drug Enforcement Administration, Special Testing and Research Laboratory, 22624 Dulles Summit Court, Dulles, VA 20166, USA.

U.S. Drug Enforcement Administration, Special Testing and Research Laboratory, 22624 Dulles Summit Court, Dulles, VA 20166, USA.

出版信息

Forensic Sci Int. 2014 Jan;234:1-6. doi: 10.1016/j.forsciint.2013.10.022. Epub 2013 Oct 31.

DOI:10.1016/j.forsciint.2013.10.022
PMID:24378294
Abstract

Differentiating methamphetamine samples produced from ephedrine and pseudoephedrine from phenyl-2-propanone precursors is critical for assigning synthetic route information for methamphetamine profiling. The use of isotope ratio mass spectrometry data is now a key component for tracking precursor information. Recent carbon (δ(13)C) isotope results from the analysis of numerous methamphetamine samples show clear differentiation for ephedrine and pseudoephedrine-produced samples compared to P2P-produced samples. The carbon isotope differences were confirmed from synthetic route precursor studies.

摘要

区分由麻黄碱和伪麻黄碱制成的甲基苯丙胺样品与由苯-2-丙酮前体制成的样品,对于确定甲基苯丙胺剖析的合成路线信息至关重要。使用同位素比率质谱数据现在是追踪前体信息的关键组成部分。最近对大量甲基苯丙胺样品分析得到的碳(δ(13)C)同位素结果表明,与由苯-2-丙酮制成的样品相比,由麻黄碱和伪麻黄碱制成的样品有明显差异。碳同位素差异已通过合成路线前体研究得到证实。

相似文献

1
The use of δ13C isotope ratio mass spectrometry for methamphetamine profiling: comparison of ephedrine and pseudoephedrine-based samples to P2P-based samples.δ13C同位素比率质谱法在甲基苯丙胺特征分析中的应用:麻黄碱和伪麻黄碱类样品与苯基-2-丙酮类样品的比较
Forensic Sci Int. 2014 Jan;234:1-6. doi: 10.1016/j.forsciint.2013.10.022. Epub 2013 Oct 31.
2
Delta(13)C, delta(15)N and delta(2)H isotope ratio mass spectrometry of ephedrine and pseudoephedrine: application to methylamphetamine profiling.麻黄碱和伪麻黄碱的δ(13)C、δ(15)N和δ(2)H同位素比率质谱分析:在甲基苯丙胺特征分析中的应用
Rapid Commun Mass Spectrom. 2009 Jul;23(13):2003-10. doi: 10.1002/rcm.4109.
3
Carbon and Nitrogen Stable Isotope Analyses of Ephedra Plant and Ephedrine Samples and Their Application For Methamphetamine Profiling.麻黄植物和麻黄碱样品的碳氮稳定同位素分析及其在甲基苯丙胺溯源中的应用
J Forensic Sci. 2018 Jul;63(4):1053-1058. doi: 10.1111/1556-4029.13692. Epub 2017 Nov 28.
4
Profiling ephedrine/pseudoephedrine and methamphetamine synthesised from benzaldehyde, nitroethane and dimethyl carbonate.分析由苯甲醛、硝基乙烷和碳酸二甲酯合成的麻黄碱/伪麻黄碱和甲基苯丙胺。
Forensic Sci Int. 2024 Jul;360:112063. doi: 10.1016/j.forsciint.2024.112063. Epub 2024 May 18.
5
Investigation of the origin of ephedrine and methamphetamine by stable isotope ratio mass spectrometry: a Japanese experience.通过稳定同位素比率质谱法对麻黄碱和甲基苯丙胺来源的调查:日本的经验
Bull Narc. 2005;57(1-2):63-78.
6
Comparative analysis of 1-phenyl-2-propanone (P2P), an amphetamine-type stimulant precursor, using stable isotope ratio mass spectrometry: presented in part as a poster at the 2nd meeting of the Joint European Stable Isotope User Meeting (JESIUM), Giens, France, September 2008.使用稳定同位素比率质谱法对苯丙胺类兴奋剂前体1-苯基-2-丙酮(P2P)进行的比较分析:部分内容作为海报在2008年9月于法国吉昂举行的第二届欧洲稳定同位素用户联合会议(JESIUM)上展示。
Sci Justice. 2009 Jun;49(2):94-101. doi: 10.1016/j.scijus.2009.03.001.
7
Methylamphetamine synthesis: does an alteration in synthesis conditions affect the δ(13) C, δ(15) N and δ(2) H stable isotope ratio values of the product?甲基苯丙胺的合成:合成条件的改变是否会影响产物的 δ(13)C、δ(15)N 和 δ(2)H 稳定同位素比值?
Drug Test Anal. 2012 May;4(5):330-6. doi: 10.1002/dta.321. Epub 2011 Sep 7.
8
[Determination of the synthetic route based on impurity profiling of methamphetamine].基于甲基苯丙胺杂质剖析确定合成路线
Wei Sheng Yan Jiu. 2008 Nov;37(6):740-4.
9
Determination of origin of ephedrine used as precursor for illicit methamphetamine by carbon and nitrogen stable isotope ratio analysis.通过碳和氮稳定同位素比率分析确定用作非法甲基苯丙胺前体的麻黄碱的来源。
Anal Chem. 2004 Jul 15;76(14):4233-6. doi: 10.1021/ac035417c.
10
Use of stable isotope ratios for profiling of industrial ephedrine samples: application of hydrogen isotope ratios in combination with carbon and nitrogen.利用稳定同位素比率分析工业麻黄碱样品:氢同位素比率与碳、氮同位素比率的联合应用
Forensic Sci Int. 2009 Aug 10;189(1-3):14-8. doi: 10.1016/j.forsciint.2009.04.011. Epub 2009 May 9.

引用本文的文献

1
Forensic investigation of falsified antimalarials using isotope ratio mass spectrometry: a pilot investigation.利用同位素比质谱法对伪造抗疟药物进行法医调查:一项初步调查。
Sci Rep. 2024 Feb 18;14(1):3995. doi: 10.1038/s41598-024-54168-9.
2
A review of the newly identified impurity profiles in methamphetamine seizures.甲基苯丙胺缉获物中新鉴定出的杂质概况综述。
Forensic Sci Int Synerg. 2020 Jun 24;2:194-205. doi: 10.1016/j.fsisyn.2020.06.004. eCollection 2020.