Liu Cuimei, Liu Peipei, Jia Wei, Fan Yingfeng
National Narcotics Laboratory, Drug Intelligence and Forensic Center of the Ministry of Public Security, Beijing, 100193, China.
J Forensic Sci. 2018 Jul;63(4):1053-1058. doi: 10.1111/1556-4029.13692. Epub 2017 Nov 28.
In this study, stable isotope ratio analysis was used to track the precursor information of methamphetamine. The δ C and δ N values of 30 nature ephedra plants, 12 synthetic ephedrine/pseudoephedrine (ephedrine), 14 natural ephedrine, and 987 seized methamphetamine samples were measured and compared. Due to different weather and earth conditions, the δ C and δ N values of ephedra plants grown in the east and the west of Inner Mongolia showed great difference. The δ N values of ephedra plants were consistent with related ephedrine extracted from them. Moreover, the criteria to infer the synthetic origin of ephedrine were set up after the analysis of natural and synthetic ephedrine samples. Finally, the precursor origins of 949 seized methamphetamine samples synthesized by Emde and Nagai method were tentatively inferred. Influenced by different preprecursors, the δ C values of seized methamphetamine samples that synthesized from P2P also showed great difference, and this result is consistent with the reported data.
本研究采用稳定同位素比率分析法追踪甲基苯丙胺的前体信息。测定并比较了30株天然麻黄植物、12份合成麻黄碱/伪麻黄碱（麻黄碱）、14份天然麻黄碱以及987份查获的甲基苯丙胺样品的δC和δN值。由于天气和土壤条件不同，内蒙古东部和西部生长的麻黄植物的δC和δN值存在很大差异。麻黄植物的δN值与其提取的相关麻黄碱一致。此外，在分析天然和合成麻黄碱样品后建立了推断麻黄碱合成来源的标准。最后，初步推断了949份采用Emde和Nagai法合成的查获甲基苯丙胺样品的前体来源。受不同前体的影响，由苯基-2-丙酮合成的查获甲基苯丙胺样品的δC值也存在很大差异，这一结果与报道的数据一致。
