Sekiya Kotaro, Watanabe Memi, Nadgir Rohini N, Buch Karen, Flower Elisa N, Kaneda Takashi, Sakai Osamu
From the *Department of Radiology, Boston Medical Center, Boston University School of Medicine, Boston, MA; †Department of Radiology, Nihon University School of Dentistry at Matsudo, Chiba, Japan; and ‡Department of Otolaryngology-Head and Neck Surgery, Boston Medical Center, Boston University School of Medicine, Boston, MA.
J Comput Assist Tomogr. 2014 Jan-Feb;38(1):9-13. doi: 10.1097/RCT.0b013e3182a77699.
Nasopharyngeal cystic lesions are commonly encountered on magnetic resonance imaging with significantly overlapped imaging characteristics. The purpose of this study was to determine the prevalence and distinguishing imaging features of cystic lesions in the nasopharynx in the largest patient series to date.
After institutional review board approval, consecutive head magnetic resonance images of 3000 patients performed at 1.5 T between June 2010 and April 2011 were retrospectively reviewed for cystic nasopharyngeal lesions. Location, size, and signal characteristic of cystic lesions were recorded. Electronic medical records were reviewed for patient demographics, symptoms, and underlying conditions.
Among 3000 patients, 6% had Tornwaldt cysts (peak prevalence, 51-60 years old) and 10% had mucous retention cysts (peak prevalence, 41-50 years old). A significant correlation between human immunodeficiency virus infection and mucous retention cysts was observed (P < 0.001).
The prevalence of Tornwaldt cysts was slightly higher than previously described in the literature. Additionally, younger and older patients had the lowest prevalence of Tornwaldt cyst, suggesting these lesions are acquired and subsequently involute with time. A significant correlation was observed between human immunodeficiency virus infection and mucous retention cysts.
鼻咽部囊性病变在磁共振成像中较为常见，其影像特征有显著重叠。本研究的目的是在迄今为止最大的患者系列中确定鼻咽部囊性病变的患病率及鉴别影像特征。
经机构审查委员会批准，对2010年6月至2011年4月期间在1.5T设备上进行的3000例患者的连续头部磁共振图像进行回顾性分析，以查找鼻咽部囊性病变。记录囊性病变的位置、大小和信号特征。查阅电子病历以获取患者人口统计学信息、症状和基础疾病情况。
在3000例患者中，6%有托恩瓦尔特囊肿（患病率高峰为51 - 60岁），10%有黏液潴留囊肿（患病率高峰为41 - 50岁）。观察到人类免疫缺陷病毒感染与黏液潴留囊肿之间存在显著相关性（P < 0.001）。
托恩瓦尔特囊肿的患病率略高于先前文献报道。此外，年龄较小和较大的患者中托恩瓦尔特囊肿的患病率最低，提示这些病变是后天获得的，随后会随时间消退。观察到人类免疫缺陷病毒感染与黏液潴留囊肿之间存在显著相关性。
