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髋臼骨折手术中两种皮肤缝合技术的前瞻性随机对照研究。

A prospective randomized comparison of two skin closure techniques in acetabular fracture surgery.

作者信息

Mudd Christopher D, Boudreau John A, Moed Berton R

机构信息

Metropolitian Orthopedics, Missouri Baptist Medical Center, 3009 Ballas Road, Suite 105 B, St. Louis, MO, 63131, USA.

出版信息

J Orthop Traumatol. 2014 Sep;15(3):189-94. doi: 10.1007/s10195-013-0282-7. Epub 2013 Dec 31.

Abstract

BACKGROUND

Recent publications have shown an infection rate of 5-7 % for acetabular fractures treated with the Kocher-Langenbeck (K-L) approach. Using metallic staples to close hip skin incisions has been considered the gold standard. The purpose of this study was to answer the following: (1) will closure of a K-L incision after acetabular fracture surgery with a running subcuticular monocryl suture, then sealing the wound with 2-octyl cyanoacrylate (OCA), result in a lower infection rate compared to metallic staple closure? (2) Do incisions closed with subcuticular monocryl and OCA exhibit decreased drainage? (3) Is there a cost difference between these two methods?

MATERIALS AND METHODS

In a prospective clinical study, 103 patients with acetabular fractures treated using the K-L approach were randomized into two groups: skin closure with metallic staples (n = 52) versus subcuticular running monocryl suture sealed with OCA (n = 51).

RESULTS

Two postoperative deep infections (4 %) in the staples group required multiple debridements; no infections developed in the OCA group. However, there was no statistical difference between the groups, (p = 0.495). There was a statistically significant difference (p = 0.032) comparing days from surgery to a dry incision favoring OCA (4.2 versus 5.85 days). The patient charge was approximately $900 greater on average in the OCA group due to the increased time in the operating room required for the subcuticular closure.

CONCLUSIONS

Closure with OCA and subcuticular monocryl showed no clinical disadvantages and appears to have a clinical advantage when compared to standard metallic staple skin closure in acetabular fracture surgery. However, additional patient costs may be incurred.

LEVEL OF EVIDENCE

II.

摘要

背景

近期发表的文献显示,采用Kocher-Langenbeck(K-L)入路治疗髋臼骨折的感染率为5%-7%。使用金属吻合钉闭合髋关节皮肤切口一直被视为金标准。本研究的目的是回答以下问题:(1)髋臼骨折手术后,使用连续皮下单丝可吸收缝线闭合K-L切口,然后用2-辛基氰基丙烯酸酯(OCA)封闭伤口,与使用金属吻合钉闭合相比,感染率是否更低?(2)用皮下单丝可吸收缝线和OCA闭合的切口引流是否减少?(3)这两种方法在成本上是否存在差异?

材料与方法

在一项前瞻性临床研究中,103例采用K-L入路治疗的髋臼骨折患者被随机分为两组:使用金属吻合钉闭合皮肤(n = 52)与使用OCA封闭的连续皮下单丝可吸收缝线(n = 51)。

结果

吻合钉组有2例术后深部感染(4%)需要多次清创;OCA组未发生感染。然而,两组之间无统计学差异(p = 0.495)。比较从手术到切口干燥的天数,OCA组有统计学显著差异(p = 0.032)(分别为4.2天和5.85天)。由于皮下闭合所需的手术室时间增加,OCA组患者费用平均高出约900美元。

结论

在髋臼骨折手术中,与标准的金属吻合钉皮肤闭合相比,使用OCA和皮下单丝可吸收缝线闭合没有临床劣势,且似乎具有临床优势。然而,可能会产生额外的患者费用。

证据级别

II级。

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