Ireland D, Cole S, Kelly P, Monaghan J M
Br J Obstet Gynaecol. 1987 May;94(5):467-72. doi: 10.1111/j.1471-0528.1987.tb03127.x.
Sections from cervical intraepithelial neoplasia (CIN 3) and stage 1b carcinoma of the cervix were stained with periodic acid-Schiff (PAS) and alcian blue to identify the presence of intracellular mucin. One out of seven specimens of CIN 3 demonstrated intracellular mucin. In a series of 33 patients with stage 1b carcinoma of the cervix with pelvic lymph node metastases, PAS demonstrated intracellular mucin staining patterns that were similar in both tumour and lymph node in most patients. In the subgroup of 23 patients classified as having squamous carcinoma, 8 (35%) demonstrated intracellular mucin to some degree and only 2 (25%) of those 8 were alive after 3 years compared with 13 of the other 15 (87%) who did not show any mucin staining (P less than 0.01).
取自宫颈上皮内瘤变（CIN 3）和1b期宫颈癌的切片用高碘酸-希夫（PAS）染色和阿尔辛蓝染色，以确定细胞内粘蛋白的存在。7例CIN 3标本中有1例显示存在细胞内粘蛋白。在一系列33例伴有盆腔淋巴结转移的1b期宫颈癌患者中，PAS显示大多数患者肿瘤和淋巴结中的细胞内粘蛋白染色模式相似。在分类为鳞状细胞癌的23例患者亚组中，8例（35%）在一定程度上显示细胞内粘蛋白，这8例中只有2例（25%）在3年后存活，而另外15例未显示任何粘蛋白染色的患者中有13例（87%）存活（P小于0.01）。
