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黏液染色在子宫颈角化型鳞状细胞癌中的临床意义

Clinical significance of mucin staining in keratinizing-type squamous cell carcinoma of the uterine cervix.

作者信息

Matsumoto Y, Ishiko O, Deguchi M, Ueda K, Ogita S, Haba T, Wakasa K

机构信息

Department of Obstetrics and Gynecology, Osaka City University Medical School, Abeno-ku, Osaka 545-8585, Japan.

出版信息

Oncol Rep. 2000 Jul-Aug;7(4):867-9. doi: 10.3892/or.7.4.867.

Abstract

Tumor tissue from 57 cases of keratinizing-type squamous cell carcinoma of the uterine cervix that had been stored in the archives of Osaka City University Hospital between May 1986 and October 1994 were stained with periodic acid-Schiff (PAS) reagent following amylase and alcian blue to identify the presence of intracellular mucin and to assess the value and significance of demonstrating the presence of mucin. Nineteen specimens (33.3%) stained positive for mucin with alcian blue or PAS following diastase. The results of mucin staining were not significant in terms of survival by Kaplan-Meier's analysis.

摘要

对1986年5月至1994年10月间存于大阪市立大学医院档案库中的57例子宫颈角化型鳞状细胞癌的肿瘤组织,先用淀粉酶和阿尔辛蓝处理,再用高碘酸 - 希夫(PAS)试剂染色,以鉴定细胞内黏液的存在,并评估显示黏液存在的价值和意义。19份标本(33.3%)在淀粉酶处理后用阿尔辛蓝或PAS染色呈黏液阳性。根据Kaplan-Meier分析,黏液染色结果在生存率方面无显著意义。

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