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糖尿病性黄斑水肿:新的有前景的治疗方法。

Diabetic macular edema: New promising therapies.

作者信息

Shamsi Hanan N Al, Masaud Jluwi S, Ghazi Nicola G

机构信息

Hanan N Al Shamsi, Jluwi S Masaud, Nicola G Ghazi, The Vitroretinal Division, King Khaled Eye Specialist Hospital, Riyadh 11462, Saudi Arabia.

出版信息

World J Diabetes. 2013 Dec 15;4(6):324-38. doi: 10.4239/wjd.v4.i6.324.

Abstract

The treatment of diabetic macular edema is rapidly evolving. The era of laser therapy is being quickly replaced by an era of pharmacotherapy. Several pharmacotherapies have been recently developed for the treatment of retinal vascular diseases such as diabetic macular edema. Several intravitreal injections or sustained delivery devices have undergone phase 3 testing while others are currently being evaluated. The results of clinical trials have shown the superiority of some of these agents to laser therapy. However, with the availability of several of these newer agents, it may be difficult to individualize treatment options especially those patients respond differently to various therapies. As such, more effort is still needed in order to determine the best treatment regimen for a given patient. In this article, we briefly summarize the major new therapeutic additions for the treatment of diabetic macular edema and allude to some future promising therapies.

摘要

糖尿病性黄斑水肿的治疗正在迅速发展。激光治疗时代正迅速被药物治疗时代所取代。最近已开发出几种用于治疗视网膜血管疾病(如糖尿病性黄斑水肿)的药物疗法。几种玻璃体内注射剂或缓释装置已进入3期试验,而其他一些正在评估中。临床试验结果表明,其中一些药物优于激光治疗。然而,随着这些新型药物的出现,可能难以实现个体化治疗方案,尤其是那些对各种疗法反应不同的患者。因此,仍需要付出更多努力来确定针对特定患者的最佳治疗方案。在本文中,我们简要总结了治疗糖尿病性黄斑水肿的主要新增治疗方法,并提及一些未来有前景的疗法。

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