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阿尔茨海默病型痴呆中的语言障碍。

Language disorders in dementia of the Alzheimer type.

作者信息

Murdoch B E, Chenery H J, Wilks V, Boyle R S

出版信息

Brain Lang. 1987 May;31(1):122-37. doi: 10.1016/0093-934x(87)90064-2.

Abstract

The language profile of a group of 18 Alzheimer patients is documented and their performance on a standard aphasia test battery compared to a group of institutionalized, nonneurologically impaired control subjects matched for age, sex, and educational level. The Alzheimer patients scored significantly lower than the controls in the areas of verbal expression, auditory comprehension, repetition, reading, and writing. Articulation abilities were the same in each group. A language deficit was evident in all Alzheimer patients. The language disorder exhibited resembled a transcortical sensory aphasia. Syntax and phonology remained relatively intact but semantic abilities were impaired. The results support the inclusion of a language deficit as a diagnostic criterion of Alzheimer's disease.

摘要

记录了一组18名阿尔茨海默病患者的语言特征,并将他们在标准失语症测试组中的表现与一组年龄、性别和教育水平相匹配的机构化、无神经功能障碍的对照受试者进行比较。在言语表达、听觉理解、复述、阅读和写作方面,阿尔茨海默病患者的得分显著低于对照组。每组的发音能力相同。所有阿尔茨海默病患者都存在明显的语言缺陷。所表现出的语言障碍类似于经皮质感觉性失语。句法和语音相对保持完整,但语义能力受损。这些结果支持将语言缺陷纳入阿尔茨海默病的诊断标准。

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