Falkenstern-Ge R F, Kimmich M, Wohlleber M, Grabner A, Friedel G, Ott G, Leuschner I, Kohlhäufl M
Division of Pulmonology, Klinik Schillerhoehe, Center for Pulmonology and Thoracic Surgery, Teaching Hospital of the University of Tuebingen, Solitude Street 18, Gerlingen, 70839 Stuttgart, Germany.
Department of Clinical Pathology, Robert Bosch Krankenhaus, Teaching Hospital of the University of Tuebingen, Auerbachstrasse 110, 70376 Stuttgart, Germany.
Case Rep Oncol Med. 2013;2013:690520. doi: 10.1155/2013/690520. Epub 2013 Nov 27.
A 30-year old woman was referred to our center because of suspicion of a primary lung tumor of the right upper lobe. Histological examination of the lung lesion revealed lung metastasis of a previously treated alveolar soft part sarcoma of the musculus vastus medialis of the right femur, which was resected 20 years ago. Alveolar soft-part sarcoma is a rare malignant tumor that occurs most often in the soft tissue of lower limbs. It is a slow-growing malignant soft tissue tumor arising in muscle tissue, usually in young adults. Due to pleural and extensive mediastinal infiltration with bilateral lung metastases, a systemic treatment with chemotherapy doxorubicin and ifosfamide was initiated. Late metastases from previously treated alveolar part sarcoma should be considered in patients with suspicious lung lesions even if surgical treatment was performed a long time ago.
一名30岁女性因疑似右上叶原发性肺肿瘤被转诊至我院。肺部病变的组织学检查显示为右股内侧肌先前治疗过的肺泡软组织肉瘤的肺转移，该肿瘤于20年前切除。肺泡软组织肉瘤是一种罕见的恶性肿瘤，最常发生于下肢软组织。它是一种生长缓慢的恶性软组织肿瘤，通常发生在年轻成人的肌肉组织中。由于胸膜和广泛的纵隔浸润伴双侧肺转移，开始采用阿霉素和异环磷酰胺进行全身化疗。即使手术治疗已过去很长时间，对于有可疑肺部病变的患者，也应考虑先前治疗过的肺泡软组织肉瘤的晚期转移。
