• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

死亡率减速与死亡率选择:一个简单模型的三个意外启示。

Mortality deceleration and mortality selection: three unexpected implications of a simple model.

机构信息

, 8128 Sewell Social Science Building, 1180 Observatory Drive, Madison, WI, 53706, USA,

出版信息

Demography. 2014 Feb;51(1):51-71. doi: 10.1007/s13524-013-0256-7.

DOI:10.1007/s13524-013-0256-7
PMID:24385199
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4559263/
Abstract

Unobserved heterogeneity in mortality risk is pervasive and consequential. Mortality deceleration-the slowing of mortality's rise with age-has been considered an important window into heterogeneity that otherwise might be impossible to explore. In this article, I argue that deceleration patterns may reveal surprisingly little about the heterogeneity that putatively produces them. I show that even in a very simple model-one that is composed of just two subpopulations with Gompertz mortality-(1) aggregate mortality can decelerate even while a majority of the cohort is frail; (2) multiple decelerations are possible; and (3) mortality selection can produce acceleration as well as deceleration. Simulations show that these patterns are plausible in model cohorts that in the aggregate resemble cohorts in the Human Mortality Database. I argue that these results challenge some conventional heuristics for understanding the relationship between selection and deceleration; undermine certain inferences from deceleration timing to patterns of social inequality; and imply that standard parametric models, assumed to plateau at most once, may sometimes badly misestimate deceleration timing-even by decades.

摘要

未被观察到的死亡率异质性普遍存在且具有重要影响。死亡率减速——即死亡率随年龄增长而减缓——被认为是探索异质性的一个重要窗口,否则这种异质性可能无法被探索。在本文中,我认为减速模式可能无法揭示产生这些模式的异质性。我表明,即使在一个非常简单的模型中——由两个具有戈特曼死亡率的亚群组成——(1)即使大多数队列都很脆弱,总死亡率也可能减速;(2)可能存在多种减速;(3)死亡率选择既可以产生加速,也可以产生减速。模拟表明,这些模式在模型队列中是合理的,这些队列在总体上类似于人类死亡率数据库中的队列。我认为,这些结果挑战了一些关于理解选择和减速之间关系的传统启发式方法;破坏了从减速时机推断社会不平等模式的某些推论;并暗示,标准参数模型(假定最多只能稳定一次)可能会严重错误估计减速时机——甚至是几十年。

相似文献

1
Mortality deceleration and mortality selection: three unexpected implications of a simple model.死亡率减速与死亡率选择:一个简单模型的三个意外启示。
Demography. 2014 Feb;51(1):51-71. doi: 10.1007/s13524-013-0256-7.
2
An underappreciated peculiarity of late-life human mortality kinetics assessed through the lens of a generalization of the Gompertz-Makeham law.通过对戈珀特-梅克汉姆定律的推广来评估老年人类死亡率动力学的一个被低估的特征。
Biogerontology. 2024 Jun;25(3):479-490. doi: 10.1007/s10522-023-10079-2. Epub 2023 Nov 25.
3
Biodemography of old-age mortality in humans and rodents.人类和啮齿动物老年死亡率的生物人口学
J Gerontol A Biol Sci Med Sci. 2015 Jan;70(1):1-9. doi: 10.1093/gerona/glu009. Epub 2014 Feb 17.
4
Rethinking mortality deceleration.重新思考死亡率减速。
Biodemography Soc Biol. 2018 Apr-Jun;64(2):127-138. doi: 10.1080/19485565.2018.1511414.
5
Have the oldest old adults ever been frail in the past? A hypothesis that explains modern trends in survival.最年长的老年人过去曾经历过身体虚弱吗?一种解释现代生存趋势的假说。
J Gerontol A Biol Sci Med Sci. 2001 Oct;56(10):B432-42. doi: 10.1093/gerona/56.10.b432.
6
Information measures and design issues in the study of mortality deceleration: findings for the gamma-Gompertz model.信息测度与死亡率减速研究中的设计问题:伽玛-戈珀兹模型的发现。
Lifetime Data Anal. 2021 Jul;27(3):333-356. doi: 10.1007/s10985-021-09518-4. Epub 2021 Feb 25.
7
Deceleration in the age pattern of mortality at older ages.老年人群死亡率年龄模式的减速。
Demography. 1998 Nov;35(4):391-412.
8
Mortality Trajectories at Extreme Old Ages: A Comparative Study of Different Data Sources on U.S. Old-Age Mortality.高龄阶段的死亡率轨迹:关于美国老年死亡率不同数据来源的比较研究
Living 100 Monogr. 2014;2014.
9
Why ageing stops: heterogeneity explains late-life mortality deceleration in nematodes.衰老为何停止:异质性解释线虫晚年死亡率减缓。
Biol Lett. 2013 Oct 2;9(5):20130217. doi: 10.1098/rsbl.2013.0217. Print 2013 Oct 23.
10
The fractionation experiment: reducing heterogeneity to investigate age-specific mortality in Drosophila.分馏实验:减少异质性以研究果蝇的年龄特异性死亡率。
Mech Ageing Dev. 1998 Nov 16;105(3):301-17. doi: 10.1016/s0047-6374(98)00102-x.

引用本文的文献

1
State-Level Education Quality and Trajectories of Cognitive Function by Race and Educational Attainment.州级教育质量与不同种族和教育程度的认知功能轨迹。
Milbank Q. 2024 Sep;102(3):765-821. doi: 10.1111/1468-0009.12709. Epub 2024 Jul 10.
2
An underappreciated peculiarity of late-life human mortality kinetics assessed through the lens of a generalization of the Gompertz-Makeham law.通过对戈珀特-梅克汉姆定律的推广来评估老年人类死亡率动力学的一个被低估的特征。
Biogerontology. 2024 Jun;25(3):479-490. doi: 10.1007/s10522-023-10079-2. Epub 2023 Nov 25.
3
Black and white differences in subjective survival expectations: An evaluation of competing mechanisms.

本文引用的文献

1
Deciphering death: a commentary on Gompertz (1825) 'On the nature of the function expressive of the law of human mortality, and on a new mode of determining the value of life contingencies'.解读死亡:对戈姆珀茨(1825年)《论表达人类死亡率规律的函数的性质,以及确定生命意外事件价值的一种新模式》的评论
Philos Trans R Soc Lond B Biol Sci. 2015 Apr 19;370(1666). doi: 10.1098/rstb.2014.0379.
2
Unobserved heterogeneity can confound the effect of education on mortality.未观察到的异质性可能会混淆教育对死亡率的影响。
Math Popul Stud. 2009 Jan 1;16(2):153-173. doi: 10.1080/08898480902790528. Epub 2009 Apr 10.
3
Scarring and mortality selection among Civil War POWs: a long-term mortality, morbidity, and socioeconomic follow-up.
主观生存期望中的黑白差异:对竞争机制的评估。
SSM Popul Health. 2023 Jan 12;21:101339. doi: 10.1016/j.ssmph.2023.101339. eCollection 2023 Mar.
4
Unobserved Population Heterogeneity and Dynamics of Health Disparities.未观察到的人群异质性与健康差距动态
Demogr Res. 2020 Jul-Dec;43:1009-1048. doi: 10.4054/demres.2020.43.34. Epub 2020 Oct 2.
5
Detecting the Effects of Early-Life Exposures: Why Fecundity Matters.检测早期暴露的影响:为什么生育力很重要。
Popul Res Policy Rev. 2019 Dec;38(6):783-809. doi: 10.1007/s11113-019-09562-x. Epub 2019 Nov 26.
6
Urinary markers of oxidative stress respond to infection and late-life in wild chimpanzees.尿液氧化应激标志物对野生黑猩猩的感染和老年期有反应。
PLoS One. 2020 Sep 11;15(9):e0238066. doi: 10.1371/journal.pone.0238066. eCollection 2020.
7
Multidimensional Mortality Selection: Why Individual Dimensions of Frailty Don't Act Like Frailty.多维死亡选择:为何衰弱的各个维度不像衰弱那样起作用。
Demography. 2020 Apr;57(2):747-777. doi: 10.1007/s13524-020-00858-8.
8
A simulation study of the role of cohort forces in mortality patterns.队列力量在死亡率模式中作用的模拟研究。
Biodemography Soc Biol. 2018 Jul-Sep;64(3-4):216-236. doi: 10.1080/19485565.2019.1568673.
9
New Trend in Old-Age Mortality: Gompertzialization of Mortality Trajectory.老年死亡率的新趋势:死亡率轨迹的戈彭策尔化。
Gerontology. 2019;65(5):451-457. doi: 10.1159/000500141. Epub 2019 May 20.
10
Robust Respondents and Lost Limitations: The Implications of Nonrandom Missingness for the Estimation of Health Trajectories.稳健应答者与遗失的限制:非随机缺失对健康轨迹估计的影响。
J Aging Health. 2019 Apr;31(4):685-708. doi: 10.1177/0898264317747079. Epub 2017 Dec 14.
内战战俘的疤痕和死亡率选择:长期死亡率、发病率和社会经济随访。
Demography. 2012 Nov;49(4):1185-206. doi: 10.1007/s13524-012-0125-9.
4
Uncrossing the U.S black-white mortality crossover: the role of cohort forces in life course mortality risk.消除美国黑-白死亡率交叉现象:队列因素在生命历程死亡率风险中的作用。
Demography. 2012 Aug;49(3):773-96. doi: 10.1007/s13524-012-0107-y.
5
The significance of education for mortality compression in the United States.教育对美国死亡率压缩的意义。
Demography. 2012 Aug;49(3):819-40. doi: 10.1007/s13524-012-0104-1.
6
Admissible mixing distributions for a general class of mixture survival models with known asymptotics.具有已知渐近性的一般类混合生存模型的可容许混合分布。
Theor Popul Biol. 2011 Aug;80(1):64-70. doi: 10.1016/j.tpb.2011.05.001. Epub 2011 May 10.
7
Heterogeneity in the Strehler-Mildvan general theory of mortality and aging.死亡率和衰老的斯特雷勒-米尔德文通论中的异质性。
Demography. 2011 Feb;48(1):267-90. doi: 10.1007/s13524-011-0013-8.
8
The implications of increased survivorship for mortality variation in aging populations.人口老龄化中生存率提高对死亡率变化的影响。
Popul Dev Rev. 2010;36(3):511-39. doi: 10.1111/j.1728-4457.2010.00344.x.
9
Cumulative index of health deficiencies as a characteristic of long life.作为长寿特征的健康缺陷累积指数。
J Am Geriatr Soc. 2007 Jun;55(6):935-40. doi: 10.1111/j.1532-5415.2007.01155.x.
10
Reproducing inequalities: luck, wallets, and the enduring effects of childhood health.重现不平等:运气、财富与童年健康的持久影响。
Demography. 2006 Nov;43(4):587-615. doi: 10.1353/dem.2006.0036.