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[播散性肺放线菌病——一种不寻常的表现]

[Disseminated pulmonary actinomycosis - an unusual presentation].

作者信息

Nowicka Urszula, Modrzewska Katarzyna, Pasik Piotr, Burakowska Barbara, Szołkowska Małgorzata, Wiatr Elżbieta

机构信息

III Klinika Chorób Płuc, Instytut Gruźlicy i Chorób Płuc w W arszawie.

出版信息

Pneumonol Alergol Pol. 2014;82(1):32-8. doi: 10.5603/PiAP.2014.0006.

Abstract

Actinomycosis is a rare, chronic infectious disease caused by anaerobic Gram-positive bacteria Actinomyces spp. They induces suppurative inflammation in tissues. They live as commensals in the oropharynx, interstitial tract and genital mucosa, causing almost exclusively endogenic infections. Beacause variable clinical course, its chronicity, quite often actinomycosis mimics rather neoplasmatic disease than infection. We present the case of 56-year old male with unusual pulmonary actinomycosis manifestation as bilateral disseminated lung nodules with systemic symptoms, after initial antitubercular treatment. Diagnosis definitely was made of histologic evaluation of lung specimen from surgical biopsy. After 7-month antibacterial treatment we have achived clinical and radiological improvement.

摘要

放线菌病是一种由厌氧革兰氏阳性菌放线菌属引起的罕见慢性感染性疾病。它们可在组织中引发化脓性炎症。它们作为共生菌存在于口咽、肠道和生殖黏膜中,几乎仅引起内源性感染。由于临床病程多变、具有慢性特点,放线菌病常常更像是肿瘤性疾病而非感染性疾病。我们报告一例56岁男性病例,其患有不寻常的肺部放线菌病,表现为双侧弥漫性肺结节并伴有全身症状,该患者在接受初始抗结核治疗后发病。通过对手术活检获取的肺标本进行组织学评估明确做出了诊断。经过7个月的抗菌治疗,我们实现了临床和影像学上的改善。

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