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[羊水来源干细胞在再生医学中的研究进展]

[Research development of amniotic fluid-derived stem cells in regenerative medicine].

作者信息

Li Chun, Li Weisong, Liu Hu, Wang Jie

机构信息

Department of Pediatric Surgery, First Affiliated Hospital of Anhui Medical University, Hefei Anhui 230022, PR China.

Department of Dermatology, Fourth Affiliated Hospital of Anhui Medical University, PR China.

出版信息

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi. 2013 Oct;27(10):1262-6.

PMID:24397143
Abstract

OBJECTIVE

To review the latest development of amniotic fluid-derived stem cells (AFSCs) in regenerative medicine, and to discuss issues related to the studies in the field of AFSCs.

METHODS

The recent articles about AFSCs were extensively reviewed. The important knowledge of AFSCs was introduced in the field of regenerative medicine, and the basic and clinical researches of AFSCs were summarized and discussed.

RESULTS

Currently, it is confirmed that AFSCs have a multi-directional differentiation capacity, therefore, they have a wide application prospect in regenerative medicine, anti-tumor, and other fields.

CONCLUSION

AFSCs will become one of the ideal seed cells in the field of regenerative medicine with extensive research value because of the advantages of easy amniotic fluid sampling, little maternal and child trauma, no tumorigenesis, and no ethical restrictions.

摘要

目的

回顾羊水来源干细胞(AFSCs)在再生医学中的最新进展,并讨论AFSCs领域研究相关问题。

方法

广泛查阅近期关于AFSCs的文章。介绍AFSCs在再生医学领域的重要知识,总结并讨论AFSCs的基础研究和临床研究。

结果

目前已证实AFSCs具有多向分化能力,因此在再生医学、抗肿瘤等领域具有广阔的应用前景。

结论

由于羊水采样容易、母婴创伤小、无致瘤性且无伦理限制等优点,AFSCs将成为再生医学领域具有广泛研究价值的理想种子细胞之一。

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