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钬激光消融术在腰椎管狭窄症中经皮椎间孔镜下神经减压的疗效

The efficacy of epiduroscopic neural decompression with Ho:YAG laser ablation in lumbar spinal stenosis.

作者信息

Lee Gun Woo, Jang Soo-Jin, Kim Jae-Do

机构信息

Department of Orthopaedic Surgery, Armed Forces Yangju Hospital, Yangju, Republic of Korea.

出版信息

Eur J Orthop Surg Traumatol. 2014 Jul;24 Suppl 1:S231-7. doi: 10.1007/s00590-013-1407-7. Epub 2014 Jan 8.

Abstract

Although epiduroscopy is one of the popular interventions for the management of lumbar spinal stenosis (LSS), only a part of these patients show improvement in pain and functional level. Consequently, the authors thought that holmium:YAG (Ho:YAG) laser can be a reasonable alternative as an adjunct of epiduroscopic procedure, but has not been thoroughly determined yet which influence is resulted by it. This study was conducted to evaluate and compare the efficacy of epiduroscopic neural decompression (END) and END with Ho:YAG laser (ELND) in patients with LSS. Forty-seven patients with LSS were enrolled, all of whom underwent END or ELND and were followed up for 2 years or more. Clinical outcomes were evaluated using the visual analog scale (VAS) for back and leg pain and the Roland Morris Disability Questionnaire (RMDQ). Procedure-related complications, especially including laser-related complications, were also evaluated. The only laser-related complication that occurred was transient mild motor paralysis in one case (3.1 %). In the END group, clinical score is exhibiting V-shaped upward trend that ended after procedure with the almost similar score obtained with preoperative status. However, in the ELND group, it is exhibiting relatively consistent improvement after procedure. There was a statistically significant improvement in the VAS and RMDQ score after 6 months after ELND procedure compared with END procedure (p = 0.01, 0.03, respectively). ELND could produce significant improvement of low back pain (LBP) at the last follow-up time (p = 0.01), but radiating pain of leg could not be improved significantly (p = 0.09). In conclusion, the current study suggests that performing Ho:YAG laser ablation concurrently with END could produce more decreased intensity of pain and prolonged effect of pain relief compared with END in LSS patients. LSS patients with LBP would be an ideal candidate for ELND, but radiating pain of LSS might not be managed effectively with ELND.

摘要

尽管硬膜外腔镜检查是治疗腰椎管狭窄症(LSS)的常用干预措施之一,但只有部分患者的疼痛和功能水平得到改善。因此,作者认为钬激光(Ho:YAG)可作为硬膜外腔镜手术的合理辅助手段,但尚未完全确定其影响。本研究旨在评估和比较硬膜外腔镜下神经减压术(END)和联合Ho:YAG激光的硬膜外腔镜下神经减压术(ELND)治疗LSS患者的疗效。纳入47例LSS患者,均接受END或ELND治疗,并随访2年以上。使用视觉模拟量表(VAS)评估腰腿痛情况,使用罗兰·莫里斯残疾问卷(RMDQ)评估临床结局。还评估了与手术相关的并发症,尤其是与激光相关的并发症。唯一发生的与激光相关的并发症是1例(3.1%)出现短暂性轻度运动麻痹。在END组,临床评分呈V形上升趋势,术后结束时与术前状态得分几乎相似。然而,在ELND组,术后显示出相对持续的改善。与END手术相比,ELND手术后6个月VAS和RMDQ评分有统计学意义的改善(分别为p = 0.01,0.03)。在最后随访时,ELND可显著改善腰痛(LBP)(p = 0.01),但腿部放射痛无显著改善(p = 0.09)。总之,本研究表明,与END相比,LSS患者在END同时进行Ho:YAG激光消融可产生更大程度的疼痛减轻和更长时间的疼痛缓解效果。LBP患者可能是ELND的理想候选者,但ELND可能无法有效治疗LSS的放射痛。

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