Yoo Byung Rhae, Son Seong, Lee Sang Gu, Kim Woo Kyung, Jung Jong Myung
Department of Neurosurgery, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea.
Neurospine. 2021 Jun;18(2):336-343. doi: 10.14245/ns.2040824.412. Epub 2021 Jun 30.
Previous literatures have demonstrated widely variable clinical results after transsacral epiduroscopic laser decompression (SELD) and the factors predicting outcomes are not yet established. Therefore, we analyzed the clinical outcome and associated predictive factors of SELD in patients with lumbar disc herniation.
Between 2015 and 2018, 82 patients who underwent single-level SELD and followed up at least 6 months were enrolled. The overall success rate (excellent or good results at final follow-up) was 58.5% according to Odom's criteria. Based on this result, patients were divided to 2 groups: a favorable group (n = 48) and an unfavorable group (n = 34). A retrospective review of the baseline characteristics and clinical outcome were conducted to reveal the predictive factors.
As expected, improvement of pain and patient satisfaction, was more favorable in the favorable group (p < 0.05). Moreover, the rate of additional procedure was lower in the favorable group (4.2%, 2 of 48 patients) than in the unfavorable group (35.3%, 12 of 34 patients) (p = 0.011). Among the various baseline characteristics, the only significant predictive factor for favorable outcome was the presence of a high-intensity zone (HIZ) on preoperative magnetic resonance imaging (50.0% [24 of 48 patients] in the favorable group vs. 11.8% [4 of 34 patients] in the unfavorable group; odds ratio, 15.67; p = 0.024).
Although SELD for lumbar disc herniation resulted in a less favorable clinical outcome than that reported in previous studies, in patients with a HIZ, SELD can be an effective minimally invasive surgery to relieve low back pain and/or leg pain.
既往文献表明,经骶管硬膜外腔镜激光减压术(SELD)后的临床结果差异很大,且尚未确定预测结果的因素。因此,我们分析了腰椎间盘突出症患者SELD的临床结果及相关预测因素。
纳入2015年至2018年间接受单节段SELD且随访至少6个月的82例患者。根据奥多姆标准,总体成功率(末次随访时结果为优或良)为58.5%。基于这一结果,将患者分为两组:预后良好组(n = 48)和预后不良组(n = 34)。对基线特征和临床结果进行回顾性分析,以揭示预测因素。
正如预期的那样,预后良好组的疼痛改善和患者满意度更高(p < 0.05)。此外,预后良好组的额外手术率(4.2%,48例患者中的2例)低于预后不良组(35.3%,34例患者中的12例)(p = 0.011)。在各种基线特征中,术前磁共振成像上存在高强度区(HIZ)是预后良好的唯一显著预测因素(预后良好组为50.0% [48例患者中的24例],预后不良组为11.8% [34例患者中的4例];优势比为15.67;p = 0.024)。
虽然腰椎间盘突出症的SELD临床结果不如既往研究报道的那样理想,但对于有HIZ的患者,SELD可以是一种有效的微创手术,用于缓解腰痛和/或腿痛。