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[疟疾]

[Malaria].

作者信息

Burchard G D

机构信息

ifi - Institut für Interdisziplinäre Medizin, Lohmühlenstr. 5, 20099, Hamburg, Deutschland,

出版信息

Internist (Berl). 2014 Feb;55(2):165-76. doi: 10.1007/s00108-013-3390-9.

DOI:10.1007/s00108-013-3390-9
PMID:24399475
Abstract

Malaria is the most important infectious disease imported by travelers and migrants from tropical and subtropical areas. It is imported quite frequently. It is a life-threatening disease. Symptoms are nonspecific and cannot easily be distinguished from a wide range of other febrile conditions. Therefore, travel history must be taken in all patients with fever of unknown origin and malaria diagnostics must be performed immediately on suspicion of malaria. Uncomplicated falciparum malaria should be treated in the hospital with either atovaquone-proguanil or with an artemisinin-based combination preparation. If there is evidence of severe malaria, the patient must be moved to an intensive care unit. The antiparasitic agent of choice is then artesunate.

摘要

疟疾是热带和亚热带地区旅行者及移民输入的最重要的传染病。其输入相当频繁。这是一种危及生命的疾病。症状不具特异性,很难与多种其他发热病症区分开来。因此,所有不明原因发热的患者都必须询问旅行史,一旦怀疑疟疾,必须立即进行疟疾诊断。非复杂性恶性疟应在医院使用阿托伐醌-氯胍或青蒿素类复方制剂进行治疗。如果有重症疟疾的迹象,患者必须转至重症监护病房。此时首选的抗寄生虫药物是青蒿琥酯。

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[Treatment of diseases acquired abroad].

本文引用的文献

1
[Severe infections : causes and management of sepsis].[严重感染:脓毒症的病因与管理]
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2
The activation of vivax malaria hypnozoites by infectious diseases.间日疟休眠子被传染病激活。
Lancet Infect Dis. 2013 Oct;13(10):900-6. doi: 10.1016/S1473-3099(13)70095-1. Epub 2013 Jun 26.
3
Hemoglobinopathies: slicing the Gordian knot of Plasmodium falciparum malaria pathogenesis.血红蛋白病:剖析恶性疟原虫发病机制的难题。
[国外获得性疾病的治疗]
Internist (Berl). 2014 Sep;55(9):1100, 1012. doi: 10.1007/s00108-014-3546-2.
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[Fever in returning travelers].[归国旅行者发热]
Internist (Berl). 2014 Mar;55(3):274-9. doi: 10.1007/s00108-013-3366-9.
PLoS Pathog. 2013;9(5):e1003327. doi: 10.1371/journal.ppat.1003327. Epub 2013 May 16.
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Human infections and detection of Plasmodium knowlesi.人类感染 knowlesi 疟原虫的情况及检测。
Clin Microbiol Rev. 2013 Apr;26(2):165-84. doi: 10.1128/CMR.00079-12.
5
GeoSentinel surveillance of illness in returned travelers, 2007-2011.2007-2011 年旅行者返回后发病的 GeoSentinel 监测。
Ann Intern Med. 2013 Mar 19;158(6):456-68. doi: 10.7326/0003-4819-158-6-201303190-00005.
6
Severe imported falciparum malaria among adults requiring intensive care: a retrospective study at the hospital for tropical diseases, London.严重的成人输入性恶性疟:伦敦热带病医院的回顾性研究。
BMC Infect Dis. 2013 Mar 5;13:118. doi: 10.1186/1471-2334-13-118.
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Fluid resuscitation of adults with severe falciparum malaria: effects on Acid-base status, renal function, and extravascular lung water.成人严重恶性疟的液体复苏:对酸碱状态、肾功能和肺外血管水的影响。
Crit Care Med. 2013 Apr;41(4):972-81. doi: 10.1097/CCM.0b013e31827466d2.
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Safety of falciparum malaria diagnostic strategy based on rapid diagnostic tests in returning travellers and migrants: a retrospective study.基于快速诊断检测的疟原虫疟疾诊断策略在返回旅行者和移民中的安全性:一项回顾性研究。
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