Rodyns'kyĭ O H, Zinov'ieva O H, Mozhunov O V, Trushenko O S
Fiziol Zh (1994). 2013;59(5):50-5.
We analyzed threshold, chronaxy and parameters of the potential of the dorsal surface (PDP) of the spinal cord (SC) in Wistar rats with experimental diabetes mellitus (DM) and intact animals. We found a decrease in the excitation threshold by 41.4% (P < 0.05), and an increase in chronaxia by 9.5% (P < 0.01), an increase of the amplitude of the N3-component by 15.8% (P < 0.05), and an increase in the duration of the afferent peak by 4.5 % (P < 0,05) and the N2-component by 10.9% (P < 0.01) responsively. We conclude that the metabolic changes under DM lead to modification of activity of the afferent pathways and interneuron pool of SC.
我们分析了实验性糖尿病（DM）的Wistar大鼠和正常动物脊髓（SC）背表面电位（PDP）的阈值、时值和参数。我们发现，兴奋阈值降低了41.4%（P < 0.05），时值增加了9.5%（P < 0.01），N3成分的幅度增加了15.8%（P < 0.05），传入峰持续时间相应增加了4.5%（P < 0.05），N2成分增加了10.9%（P < 0.01）。我们得出结论，糖尿病状态下的代谢变化导致脊髓传入通路和中间神经元池的活动发生改变。
