Pushkarev Iu P
Probl Endokrinol (Mosk). 1978 Jul-Aug;24(4):64-7.
The intensity of the monosynaptic spinal cord reflex was studied in rats with prolonged severe diabetes mellitus and with that of moderate severity, of short duration. Methods of H-reflex and M-response of the motor nerves and muscles were used. The number of motor neurons taking part in the reflex proved to be less in diabetic animals; rhythmic H-reflex was depressed. These disturbances were primarily connected with the functional changes of the primary afferent terminals of the segmental spinal cord level. In animals with moderately severe diabetes the operative mediator fraction was readily exhausted and the mediator emission decreased. Besides, animals with a severe form of alloxan diabetes displayed postsynaptic disturbances. A positive correlation between the extent of the H-reflex depression and the severity (duration) of alloxan diabetes was demonstrated.
在患有长期严重糖尿病以及中度严重、病程较短的糖尿病大鼠中，研究了单突触脊髓反射的强度。采用了运动神经和肌肉的H反射及M反应方法。结果表明，参与反射的运动神经元数量在糖尿病动物中较少；节律性H反射受到抑制。这些干扰主要与脊髓节段水平的初级传入终末的功能变化有关。在中度严重糖尿病的动物中，手术介质部分很容易耗尽，介质释放减少。此外，患有严重形式的四氧嘧啶糖尿病的动物表现出突触后干扰。证实了H反射抑制程度与四氧嘧啶糖尿病的严重程度（病程）之间存在正相关。
