Haggerty Christopher M, Yoganathan Ajit P, Fogel Mark A
1 The Wallace H. Coulter Department of Biomedical Engineering, Georgia Institute of Technology & Emory University, Atlanta, United States of America.
2 Department of Pediatrics, Division of Cardiology, The Children's Hospital of Philadelphia, The University of Pennsylvania School of Medicine, Philadelphia, United States of America.
Cardiol Young. 2013 Dec;23(6):818-23. doi: 10.1017/S1047951113001637.
The Fontan procedure, although an imperfect solution for children born with a single functional ventricle, is the only reconstruction at present short of transplantation. The haemodynamics associated with the total cavopulmonary connection, the modern approach to Fontan, are severely altered from the normal biventricular circulation and may contribute to the long-term complications that are frequently noted. Through recent technological advances, spear-headed by advances in medical imaging, it is now possible to virtually model these surgical procedures and evaluate the patient-specific haemodynamics as part of the pre-operative planning process. This is a novel paradigm with the potential to revolutionise the approach to Fontan surgery, help to optimise the haemodynamic results, and improve patient outcomes. This review provides a brief overview of these methods, presents preliminary results of their clinical usage, and offers insights into its potential future directions.
尽管Fontan手术对于单心室患儿来说并非完美解决方案,但它是目前除移植外唯一的重建方法。全腔静脉肺动脉连接术(现代Fontan手术方法)相关的血流动力学与正常双心室循环相比发生了严重改变,可能导致常见的长期并发症。随着医学成像技术的进步引领的最新技术发展,现在可以对这些手术进行虚拟建模,并在术前规划过程中评估患者特异性血流动力学。这是一种新的范例,有可能彻底改变Fontan手术方法,有助于优化血流动力学结果并改善患者预后。本综述简要概述了这些方法,介绍了其临床应用的初步结果,并探讨了其未来潜在的发展方向。