Nepal Ashwini Kumar, Gelal Basanta, Mehta Kisundeo, Lamsal Madhab, Pokharel Paras Kumar, Baral Nirmal
Department of Biochemistry, Faculty of Medicine, B,P, Koirala Institute of Health Sciences, Dharan, Nepal.
BMC Res Notes. 2014 Jan 9;7:18. doi: 10.1186/1756-0500-7-18.
Zinc deficiency is a major public health problem in many developing countries including Nepal. The present study was designed to assess the prevalence of zinc deficiency and to study the association of zinc deficiency with anthropometric and socio-demographic variables, in school children of eastern Nepal.
This cross-sectional study included total 125 school children of age group 6-12 years from Sunsari and Dhankuta districts of eastern Nepal. Plasma zinc level was estimated by Flame Atomic Absorption Spectroscopy.
The Median interquartile range (IQR) values of zinc in the two districts Sunsari and Dhankuta were 5.9 (4.4, 7.9) μmol/L and 5.8 (4.3, 8.4) μmol/L respectively. A total of 55 children (87.3%) in Sunsari and 52 (83.9%) in Dhankuta had zinc deficiency, no significant difference was observed in the Median (IQR) plasma zinc levels (p = 0.9) and zinc deficiency patterns (p = 0.3) of the two districts. Significant differences were observed in the plasma zinc levels (p = 0.02) and zinc deficiency patterns (p = 0.001), of the school children having age groups 6-8 years than in 9-10 and 11-12 years of age, and zinc deficiency patterns between male and female school children (p = 0.04) respectively.
The present study showed higher prevalence of zinc deficiency among school children in eastern Nepal. In our study, zinc deficiency was associated with both sex and age. The findings from the present study will help to populate data for policy implementation regarding consumption and supplementation of zinc.
锌缺乏是包括尼泊尔在内的许多发展中国家的一个主要公共卫生问题。本研究旨在评估尼泊尔东部学童锌缺乏的患病率,并研究锌缺乏与人体测量和社会人口统计学变量之间的关联。
这项横断面研究共纳入了尼泊尔东部孙萨里和丹库塔地区125名6至12岁的学童。采用火焰原子吸收光谱法测定血浆锌水平。
孙萨里和丹库塔两个地区锌的中位数四分位数间距(IQR)值分别为5.9(4.4,7.9)μmol/L和5.8(4.3,8.4)μmol/L。孙萨里共有55名儿童(87.3%)、丹库塔共有52名儿童(83.9%)存在锌缺乏,两个地区的血浆锌水平中位数(IQR)(p = 0.9)和锌缺乏模式(p = 0.3)未观察到显著差异。6至8岁的学童与9至10岁和11至12岁的学童相比,血浆锌水平(p = 0.02)和锌缺乏模式(p = 0.001)存在显著差异,男、女学童之间的锌缺乏模式也存在显著差异(p = 0.04)。
本研究表明尼泊尔东部学童锌缺乏的患病率较高。在我们的研究中,锌缺乏与性别和年龄均有关联。本研究结果将有助于为锌的消费和补充方面的政策实施提供数据支持。