Visual Cognition Laboratory, Department of Medicine, University of Fribourg, Fribourg, Switzerland; and Center for Cognition, University of Fribourg, Fribourg, Switzerland.
J Neurophysiol. 2014 May;111(9):1717-20. doi: 10.1152/jn.00323.2013. Epub 2014 Jan 8.
Recently, the functional specialization of prefrontal areas of the brain, and, specifically, the functional dissociation of the orbitofrontal cortex (OFC) and the anterior cingulate cortex (ACC), during decision making have become a particular focus of research. A number of neuropsychological and lesion studies have shown that the OFC and ACC have dissociable functions in various dimensions of decision making, which are supported by their different anatomical connections. A recent single-neuron study, however, described a more complex picture of the functional dissociation between these two frontal regions during decision making. Here, I discuss the results of that study and consider alternative interpretations in connection with other findings.
最近，大脑前额叶区域的功能专门化，特别是眶额皮层 (OFC) 和前扣带皮层 (ACC) 在决策过程中的功能分离，已成为研究的一个特别关注点。许多神经心理学和损伤研究表明，OFC 和 ACC 在决策的各个维度上具有可分离的功能，这得到了它们不同解剖连接的支持。然而，最近的一项单细胞研究描述了这两个前额区域在决策过程中功能分离的更为复杂的情况。在这里，我将讨论该研究的结果，并结合其他发现考虑替代解释。
