Department of Mental Health, Bloomberg School of Public Health, The Johns Hopkins University, Baltimore, Maryland.
JAMA Psychiatry. 2014 Mar;71(3):273-80. doi: 10.1001/jamapsychiatry.2013.3579.
Our understanding of how mental and physical disorders are associated and contribute to health outcomes in populations depends on accurate ascertainment of the history of these disorders. Recent studies have identified substantial discrepancies in the prevalence of mental disorders among adolescents and young adults depending on whether the estimates are based on retrospective reports or multiple assessments over time. It is unknown whether such discrepancies are also seen in midlife to late life. Furthermore, no previous studies have compared lifetime prevalence estimates of common physical disorders such as diabetes mellitus and hypertension ascertained by prospective cumulative estimates vs retrospective estimates.
To examine the lifetime prevalence estimates of mental and physical disorders during midlife to late life using both retrospective and cumulative evaluations.
DESIGN, SETTING, AND PARTICIPANTS: Prospective population-based survey (Baltimore Epidemiologic Catchment Area Survey) with 4 waves of interviews of 1071 community residents in Baltimore, Maryland, between 1981 and 2005.
Lifetime prevalence of selected mental and physical disorders at wave 4 (2004-2005), according to both retrospective data and cumulative evaluations based on 4 interviews from wave 1 to wave 4. RESULTS Retrospective evaluations substantially underestimated the lifetime prevalence of mental disorders as compared with cumulative evaluations. The respective lifetime prevalence estimates ascertained by retrospective and cumulative evaluations were 4.5% vs. 13.1% for major depressive disorder, 0.6% vs. 7.1% for obsessive-compulsive disorder, 2.5% vs. 6.7% for panic disorder, 12.6% vs. 25.3% for social phobia, 9.1% vs. 25.9% for alcohol abuse or dependence, and 6.7% vs. 17.6% for drug abuse or dependence. In contrast, retrospective lifetime prevalence estimates of physical disorders ascertained at wave 4 were much closer to those based on cumulative data from all 4 waves. The respective prevalence estimates ascertained by the 2 methods were 18.2% vs. 20.2% for diabetes, 48.4% vs. 55.4% for hypertension, 45.8% vs. 54.0% for arthritis, 5.5% vs. 7.2% for stroke, and 8.4% vs. 10.5% for cancer.
One-time, cross-sectional population surveys may consistently underestimate the lifetime prevalence of mental disorders. The population burden of mental disorders may therefore be substantially higher than previously appreciated.
我们对精神和身体障碍在人群中的关联及其对健康结果的影响的理解取决于对这些障碍病史的准确确定。最近的研究表明,根据回顾性报告或随时间多次评估,青少年和年轻人的精神障碍患病率存在很大差异。目前尚不清楚这种差异是否也存在于中年到晚年。此外,以前的研究没有比较通过前瞻性累积评估与回顾性评估确定的常见躯体疾病(如糖尿病和高血压)的终生患病率估计值。
使用回顾性和累积评估方法检查中年到晚年精神和身体障碍的终生患病率估计值。
设计、地点和参与者:前瞻性基于人群的调查(巴尔的摩流行病学抽样区调查),对马里兰州巴尔的摩的 1071 名社区居民进行了 4 波访谈,时间为 1981 年至 2005 年。
根据第 4 波(2004-2005 年)的回顾性数据和基于第 1 波至第 4 波的 4 次访谈的累积评估,确定选定的精神和身体障碍的终生患病率。结果:与累积评估相比,回顾性评估大大低估了精神障碍的终生患病率。通过回顾性和累积评估确定的各自终生患病率估计值分别为:重度抑郁症 4.5% vs. 13.1%,强迫症 0.6% vs. 7.1%,惊恐障碍 2.5% vs. 6.7%,社交恐惧症 12.6% vs. 25.3%,酒精滥用或依赖 9.1% vs. 25.9%,药物滥用或依赖 6.7% vs. 17.6%。相比之下,第 4 波通过回顾性确定的躯体疾病终生患病率与基于 4 波累积数据的患病率更为接近。这两种方法确定的患病率估计值分别为:糖尿病 18.2% vs. 20.2%,高血压 48.4% vs. 55.4%,关节炎 45.8% vs. 54.0%,中风 5.5% vs. 7.2%,癌症 8.4% vs. 10.5%。
一次性的横断面人群调查可能会持续低估精神障碍的终生患病率。因此,精神障碍的人群负担可能比之前认为的要高得多。