• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

手术治疗黏膜黑色素瘤的自然病史。

Natural history of surgically treated mucosal melanoma.

作者信息

Wong J H, Cagle L A, Storm F K, Morton D L

出版信息

Am J Surg. 1987 Jul;154(1):54-7. doi: 10.1016/0002-9610(87)90289-3.

DOI:10.1016/0002-9610(87)90289-3
PMID:2440332
Abstract

Thirty-three patients with melanoma arising in a mucosal site were reviewed. Sixteen patients were treated either with abdominoperineal resection or radical vulvectomy and superficial inguinal lymphadenectomy. Three patients were treated palliatively. Fourteen patients were treated conservatively with local excision, wide local excision, and radiation therapy. One patient received systemic chemotherapy and radiation therapy. Local recurrence developed in seven patients. The overall survival rate was poor. Neither local control nor survival appeared to be influenced by the initial surgical approach.

摘要

对33例发生于黏膜部位的黑色素瘤患者进行了回顾性研究。16例患者接受了腹会阴联合切除术或根治性外阴切除术及浅表腹股沟淋巴结清扫术。3例患者接受了姑息治疗。14例患者接受了局部切除、广泛局部切除及放射治疗的保守治疗。1例患者接受了全身化疗及放射治疗。7例患者出现局部复发。总体生存率较差。局部控制和生存率似乎均未受到初始手术方式的影响。

相似文献

1
Natural history of surgically treated mucosal melanoma.手术治疗黏膜黑色素瘤的自然病史。
Am J Surg. 1987 Jul;154(1):54-7. doi: 10.1016/0002-9610(87)90289-3.
2
Patterns of failure in anorectal melanoma. A guide to surgical therapy.肛管直肠黑色素瘤的失败模式。手术治疗指南。
Arch Surg. 1990 Mar;125(3):313-6. doi: 10.1001/archsurg.1990.01410150035007.
3
[Value of inguinal lymph node excision in anorectal melanoma].[腹股沟淋巴结切除术在肛管直肠黑色素瘤中的价值]
Zentralbl Chir. 1996;121(6):483-6.
4
Sphincter-sparing local excision and hypofractionated radiation therapy for anorectal melanoma: a 20-year experience.肛门直肠黑色素瘤的保留括约肌局部切除和低分割放疗:20 年经验。
Cancer. 2011 Oct 15;117(20):4747-55. doi: 10.1002/cncr.26088. Epub 2011 Mar 28.
5
Surgical therapy for anorectal melanoma.肛管直肠黑色素瘤的手术治疗
J Am Coll Surg. 2003 Feb;196(2):206-11. doi: 10.1016/S1072-7515(02)01538-7.
6
[Primary anorectal melanoma. Apropos of 19 cases].[原发性肛管直肠黑色素瘤。附19例报告]
J Chir (Paris). 1997 May;134(1):3-8.
7
Anorectal malignant melanoma: treatment with surgery or radiation therapy, or both.肛管直肠恶性黑色素瘤:手术或放射治疗,或两者联合治疗。
Can J Surg. 2003 Oct;46(5):345-9.
8
[Anorectal malignant melanoma : Treatment recommendations].[肛管直肠恶性黑色素瘤:治疗建议]
Chirurg. 2016 Sep;87(9):768-774. doi: 10.1007/s00104-016-0242-x.
9
Sphincter-sparing local excision and adjuvant radiation for anal-rectal melanoma.保留括约肌的局部切除及辅助放疗治疗肛管直肠黑色素瘤
J Clin Oncol. 2002 Dec 1;20(23):4555-8. doi: 10.1200/JCO.2002.03.002.
10
Natural history and treatment of mucosal melanoma.黏膜黑色素瘤的自然病史与治疗
J Surg Oncol. 1989 Aug;41(4):222-5. doi: 10.1002/jso.2930410406.

引用本文的文献

1
Treatment of recurrent mucosal melanoma of the oral cavity with topical imiquimod and pembrolizumab achieves complete histopathologic remission.局部应用咪喹莫特和帕博利珠单抗治疗复发性口腔黏膜黑色素瘤可实现完全组织病理学缓解。
J Immunother Cancer. 2021 Oct;9(10). doi: 10.1136/jitc-2020-001219.
2
Extensive malignant melanoma of the oral cavity: a rare occurrence.口腔广泛性恶性黑色素瘤:一种罕见病例。
Autops Case Rep. 2021 Aug 20;11:e2021299. doi: 10.4322/acr.2021.299. eCollection 2021.
3
NCDB Analysis of Melanoma 2004-2015: Epidemiology and Outcomes by Subtype, Sociodemographic Factors Impacting Clinical Presentation, and Real-World Survival Benefit of Immunotherapy Approval.
2004 - 2015年黑色素瘤的国家癌症数据库分析:按亚型分类的流行病学及预后、影响临床表现的社会人口统计学因素以及免疫疗法获批后的实际生存获益
Cancers (Basel). 2021 Mar 22;13(6):1455. doi: 10.3390/cancers13061455.
4
SYNCHRONOUS ANAL MELANOMA AND COLON ADENOCARCINOMA: CASE REPORT AND REVIEW OF DIAGNOSIS AND MANAGEMENT.同步性肛管黑色素瘤和结肠腺癌:病例报告及诊断与治疗综述
Arq Bras Cir Dig. 2016 Nov-Dec;29(4):293-295. doi: 10.1590/0102-6720201600040020.
5
Retrospective multicenter evaluation of patients diagnosed with mucosal melanoma: a study of Anatolian Society of Medical Oncology.黏膜黑色素瘤确诊患者的回顾性多中心评估:一项安纳托利亚医学肿瘤学会的研究
Tumour Biol. 2016 Sep;37(9):12033-12038. doi: 10.1007/s13277-016-5076-0. Epub 2016 May 12.
6
Oral malignant melanoma: a rare case with unusual clinical presentation.口腔恶性黑色素瘤:一例临床表现不寻常的罕见病例。
Pan Afr Med J. 2015 Oct 9;22:113. doi: 10.11604/pamj.2015.22.113.7773. eCollection 2015.
7
Evaluation of the prognostic impact of postoperative adjuvant radiotherapy on head and neck mucosal melanoma: a meta-analysis.术后辅助放疗对头颈部黏膜黑色素瘤预后影响的评估:一项荟萃分析。
BMC Cancer. 2015 Oct 21;15:758. doi: 10.1186/s12885-015-1750-7.
8
A rare case of rynopharyngeal melanoma.一例罕见的鼻咽黑色素瘤。
Dent Res J (Isfahan). 2012 Dec;9(Suppl 2):S229-32. doi: 10.4103/1735-3327.109767.
9
Malignant mucosal melanoma of the paranasal sinuses: Two case presentations.鼻窦恶性黏膜黑色素瘤:两例病例报告。
World J Clin Oncol. 2011 Oct 10;2(10):344-7. doi: 10.5306/wjco.v2.i10.344.
10
Review.综述
Gastroenterol Hepatol (N Y). 2008 Nov;4(11):797-8.