学龄儿童的角膜生物力学特性及相关因素
Corneal biomechanical properties and associated factors in school-age children.
作者信息
Huang Yuqiang, Lin Shibin, Ma Di, Wang Zhenmao, Du Yali, Lu Xuehui, Zhang Mingzhi
机构信息
Shantou University, The Chinese University of Hong Kong Joint Shantou International Eye Center, Shantou 515041, China.
出版信息
Eye Sci. 2013 Mar;28(1):34-9.
PURPOSE
To study and analyze the correlation among corneal biomechanical properties and associated factors including central corneal thickness (CCT), corneal curvature (CT), and intraocular pressure (IOP) in school-age children.
METHODS
A cross sectional investigation was conducted. An ocular response analyzer was utilized to assess the corneal biomechanical properties, such as corneal hysteresis and corneal resistance factors, in children of school age. Multivariate regression analysis was used to investigate the relationship between corneal biomechanical properties and other ocular parameters including CCT, corneal curvature (k1 and k2), and IOP. The right eyes of all subjects were selected for statistical analysis.
RESULTS
A total of 571 children were enrolled: 303 male and 268 female, with an average age of 10.47 +/- 1.0 years. The mean value of corneal hysteresis was 10.98 +/- 1.78 mmHg, corneal resistance factor was 11.46 +/-1.69 mmHg, and CCT was 556.01 +/- 28.97, microm.
CONCLUSION
The feasibility of corneal biomechanical detection in school age children was validated. This study provides fundamental data on corneal biomechanical properties in school-age children and associated factors.
目的
研究并分析学龄儿童角膜生物力学特性与包括中央角膜厚度（CCT）、角膜曲率（CT）和眼压（IOP）在内的相关因素之间的相关性。
方法
进行横断面调查。使用眼反应分析仪评估学龄儿童的角膜生物力学特性，如角膜滞后和角膜阻力因子。采用多元回归分析研究角膜生物力学特性与其他眼部参数之间的关系，这些参数包括CCT、角膜曲率（k1和k2）和IOP。所有受试者的右眼被选作统计分析。
结果
共纳入571名儿童，其中男性303名，女性268名，平均年龄为10.47±1.0岁。角膜滞后的平均值为10.98±1.78 mmHg，角膜阻力因子为11.46±1.69 mmHg，CCT为556.01±28.97微米。
结论
验证了学龄儿童角膜生物力学检测的可行性。本研究提供了学龄儿童角膜生物力学特性及相关因素的基础数据。
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