Baharuddin Mohd Yusof, Salleh Sh-Hussain, Suhasril Andril Arafat, Zulkifly Ahmad Hafiz, Lee Muhammad Hisyam, Omar Mohd Afian, Abd Kader Ab Saman, Mohd Noor Alias, A Harris Arief Ruhullah, Abdul Majid Norazman
Department of Biomedical Engineering, Faculty of Engineering, University of Malaya, Lembah Pantai, Kuala Lumpur, Malaysia; Centre for Biomedical Engineering Transportation Research Alliance, Universiti Teknologi Malaysia, Skudai, Johor, Malaysia.
Artif Organs. 2014 Jul;38(7):603-8. doi: 10.1111/aor.12222. Epub 2014 Jan 10.
Total hip arthroplasty is a flourishing orthopedic surgery, generating billions of dollars of revenue. The cost associated with the fabrication of implants has been increasing year by year, and this phenomenon has burdened the patient with extra charges. Consequently, this study will focus on designing an accurate implant via implementing the reverse engineering of three-dimensional morphological study based on a particular population. By using finite element analysis, this study will assist to predict the outcome and could become a useful tool for preclinical testing of newly designed implants. A prototype is then fabricated using 316L stainless steel by applying investment casting techniques that reduce manufacturing cost without jeopardizing implant quality. The finite element analysis showed that the maximum von Mises stress was 66.88 MPa proximally with a safety factor of 2.39 against endosteal fracture, and micromotion was 4.73 μm, which promotes osseointegration. This method offers a fabrication process of cementless femoral stems with lower cost, subsequently helping patients, particularly those from nondeveloped countries.
全髋关节置换术是一种蓬勃发展的骨科手术,创造了数十亿美元的收入。与植入物制造相关的成本逐年增加,这种现象给患者带来了额外的费用负担。因此,本研究将专注于通过基于特定人群实施三维形态学研究的逆向工程来设计精确的植入物。通过使用有限元分析,本研究将有助于预测结果,并可能成为新设计植入物临床前测试的有用工具。然后采用熔模铸造技术用316L不锈钢制造一个原型,该技术在不影响植入物质量的情况下降低了制造成本。有限元分析表明,近端最大冯·米塞斯应力为66.88MPa,抗骨内膜骨折的安全系数为2.39,微动为4.73μm,这有利于骨整合。这种方法提供了一种低成本的非骨水泥股骨柄制造工艺,从而帮助患者,特别是来自不发达国家的患者。