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酷似结节病的纤维性纵隔炎。

Fibrosing mediastinitis mimicking sarcoidosis.

作者信息

Ferrer Galván Marta, Rodríguez Portal José Antonio, Serrano Gorarredona María Pilar, Gómez Izquierdo Lourdes

机构信息

Medical-Surgical Unit of Respiratory Diseases, IBIS, CIBERES, University Hospital Virgen del Rocio, Seville, Spain.

出版信息

Clin Respir J. 2015 Jan;9(1):125-8. doi: 10.1111/crj.12107. Epub 2014 May 15.

Abstract

Fibrosing mediastinitis (FM), also called sclerosing mediastinitis or mediastinal fibrosis, is a rare disease characterized by excessive fibrotic reaction in the mediastinum and may compromise the airway, the great vessels and other mediastinal structures, with a morbidity directly related to the location and extent of fibrosis. The cause is not always known but is often the result of a granulomatous disease, most often the histoplasmosis. We report a 43-year-old woman with a history of tuberculosis infection 23 years ago. She attended the pulmonology clinic for cough and dyspnea. Physical examination revealed jugular venous distention at 90°. In computed tomography scan of the chest with contrast (c/c), we observed a mediastinal nodal cast provoking cava compression and obliteration of main and intermediary right lobar bronchus. The pathological examination was FM.

摘要

纤维性纵隔炎(FM),也称为硬化性纵隔炎或纵隔纤维化,是一种罕见疾病,其特征为纵隔内出现过度纤维化反应,可能会累及气道、大血管及其他纵隔结构,发病率与纤维化的部位和范围直接相关。病因通常不明,但往往是肉芽肿性疾病的结果,最常见的是组织胞浆菌病。我们报告一名43岁女性,有23年前结核感染史。她因咳嗽和呼吸困难到肺科门诊就诊。体格检查发现颈静脉在90°时扩张。在胸部增强计算机断层扫描(c/c)中,我们观察到纵隔淋巴结铸型导致腔静脉受压以及右肺上叶主支气管和中间支气管闭塞。病理检查为纤维性纵隔炎。

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