Nakipova O V, Kokoz Iu M, Freĭdin A A, Safronova V G, Lazarev A V
Fiziol Zh SSSR Im I M Sechenova. 1987 Apr;73(4):492-8.
The experiments on frog atra tuberculae revealed that insulin could induce biphasic changes of calcium currents of different directions. The current is inhibited with hormone due to a decrease both in the conductivity of channel system and reversal potential. In some cases prior to inhibition of calcium current, a short rise of this current occurred (3-6 min) induced by increased reversal potential. Possible mechanisms of insulin electrophysiological effects are discussed.
对青蛙结节性心房的实验表明,胰岛素可诱导不同方向钙电流的双相变化。由于通道系统的电导率和反转电位降低,电流会被激素抑制。在某些情况下,在钙电流被抑制之前,会出现由反转电位升高引起的该电流短暂上升(3 - 6分钟)。文中讨论了胰岛素电生理效应的可能机制。