Wu Hong-Ming, Tzeng Chii-Ruey, Chen Chi-Hung, Chen Pi-Hua
Department of Obstetrics and Gynecology, Center for Reproductive Medicine, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan.
Department of Obstetrics and Gynecology, Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan.
Taiwan J Obstet Gynecol. 2013 Dec;52(4):512-5. doi: 10.1016/j.tjog.2013.10.010.
This study investigated the occurrence of peritoneal fluid in women undergoing intrauterine insemination (IUI) and its correlation with the stage of pelvic endometriosis and its influence on pregnancy outcomes.
A retrospective case-control design was used to recruit 272 infertile women with pelvic endometriosis. The treatment protocol consisted of controlled ovarian hyperstimulation with downregulation and gonadotropin for IUI treatment following ultrasound and laparoscopic intervention. The amount and color of the peritoneal fluid were determined during laparoscopy.
The mean amount of peritoneal fluid with pelvic endometriosis that was detected using transvaginal ultrasound was ~ 15.1 mL. Women whose cycles contained more peritoneal fluid had significantly lower pregnancy rates (17.2% and 31.3%, respectively). The total clinical pregnancy rate was not significantly different between the two groups with reddish and yellowish peritoneal fluid who had pelvic endometriosis.
Pelvic endometriosis and peritoneal fluid, detected through vaginal ultrasound, have negative effects on the pregnancy outcome of IUI treatment.
本研究调查了接受宫内人工授精（IUI）的女性腹腔液的出现情况及其与盆腔子宫内膜异位症分期的相关性，以及其对妊娠结局的影响。
采用回顾性病例对照设计，招募了272例患有盆腔子宫内膜异位症的不孕女性。治疗方案包括在超声和腹腔镜干预后，采用降调节和促性腺激素进行控制性卵巢过度刺激以进行IUI治疗。在腹腔镜检查期间确定腹腔液的量和颜色。
经阴道超声检测到的盆腔子宫内膜异位症患者腹腔液平均量约为15.1 mL。周期中腹腔液较多的女性妊娠率显著较低（分别为17.2%和31.3%）。盆腔子宫内膜异位症患者腹腔液呈红色和黄色的两组之间总临床妊娠率无显著差异。
经阴道超声检测到的盆腔子宫内膜异位症和腹腔液对IUI治疗的妊娠结局有负面影响。
