Goetz Michal, Schwabova Jaroslava, Hlavka Zdenek, Ptacek Radek, Zumrova Alena, Hort Vladimír, Doyle Robert
1 Charles University in Prague, Czech Republic.
2 General University Hospital, Prague, Czech Republic.
J Atten Disord. 2017 Feb;21(3):190-199. doi: 10.1177/1087054713517745. Epub 2016 Jul 27.
We examined the presence of cerebellar symptoms in ADHD and their association with behavioral markers of this disorder.
Sixty-two children with ADHD and 62 typically developing (TD) children were examined for cerebellar symptoms using the ataxia rating scale and tested using Conners' Continuous Performance Test.
Children with ADHD had significantly more cerebellar symptoms compared with the TD children. Cerebellar symptom scores decreased with age in the ADHD group; in the TD group remained stable. In both groups, cerebellar symptoms were associated with parent-rated hyperactive/impulsive symptoms, variability of response time standard error (RT-SE) and increase of RT-SE as the test progresses. More variables were associated with cerebellar symptoms in the ADHD group including omission errors, overall RT-SE and its increase for prolonged interstimulus intervals.
Our results highlight the importance of research into motor functions in children with ADHD and indicate a role for cerebellar impairment in this disorder.
我们研究了注意缺陷多动障碍(ADHD)患儿中是否存在小脑症状及其与该疾病行为指标的关联。
使用共济失调评定量表对62名ADHD患儿和62名发育正常(TD)儿童进行小脑症状检查,并使用康纳斯连续作业测试进行测试。
与TD儿童相比,ADHD患儿的小脑症状明显更多。ADHD组中小脑症状评分随年龄降低;TD组则保持稳定。在两组中,小脑症状均与家长评定的多动/冲动症状、反应时间标准误差(RT-SE)的变异性以及测试过程中RT-SE的增加有关。ADHD组中有更多变量与小脑症状相关,包括遗漏错误、总体RT-SE及其在较长刺激间隔时的增加。
我们的结果凸显了对ADHD患儿运动功能研究的重要性,并表明小脑损伤在该疾病中起一定作用。