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A human monoclonal antibody against HLA-A25.

作者信息

Kosinski S, Ferrara G B, Yang S Y, Hämmerling U

出版信息

Tissue Antigens. 1987 Apr;29(4):177-83. doi: 10.1111/j.1399-0039.1987.tb01573.x.

DOI:10.1111/j.1399-0039.1987.tb01573.x
PMID:2441487
Abstract

We are reporting the production and characterization of a human monoclonal antibody recognizing antigen HLA-25. The antibody was developed by a line transformed in vitro by the Epstein-Barr virus. The immune B lymphocytes for transformation were generated by planned immunization of a volunteer with repeated doses of allogenic peripheral blood lymphocytes of one donor over the course of 7 years. The antibody showed correlation with A25 antigen on a panel of 244 individuals tested by microcytotoxicity. The antibody showed neither cytotoxic reactivity nor CYNAP phenomenon with antigens of HLA-10 CREG.

摘要

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引用本文的文献

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A human monoclonal antibody recognizing a determinant shared by a group of HLA-B locus antigens associated with HLA-Bw6.一种识别一组与HLA - Bw6相关的HLA - B位点抗原所共有的决定簇的人单克隆抗体。
Immunogenetics. 1987;26(1-2):120-2. doi: 10.1007/BF00345466.