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人类丘脑底核的解剖学:一项联合形态测量学研究。

Anatomy of the human subthalamic nucleus: a combined morphometric study.

作者信息

Mavridis Ioannis, Boviatsis Efstathios, Anagnostopoulou Sophia

机构信息

Department of Anatomy, University of Athens, School of Medicine, Mikras Assias street 75, Goudi, 11527 Athens, Greece.

2nd Department of Neurosurgery, Attikon Hospital, University of Athens, School of Medicine, Rimini Street 1, Haidari, 12462 Athens, Greece.

出版信息

Anat Res Int. 2013;2013:319710. doi: 10.1155/2013/319710. Epub 2013 Dec 15.

DOI:10.1155/2013/319710
PMID:24416591
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3876692/
Abstract

Purpose. Our purpose was to provide a combined clinically oriented study focused on the detailed anatomy of the human STN, with great respect to its targeting. Methods. For our imaging study, we used cerebral magnetic resonance images (MRIs) from 26 neurosurgical patients and for our anatomic study 32 cerebral hemispheres from 18 normal brains from cadaver donors. We measured and analyzed the STN dimensions (based on its stereotactic coordinates). Results. At stereotactic level Z = -4, the STN length was 7.7 mm on MRIs and 8.1 mm in anatomic specimens. Its width was 6 mm on MRIs and 6.3 mm in anatomic specimens. The STN was averagely visible in 3.2 transverse MRI slices and its maximum dimension was 8.5 mm. The intercommissural distance was 26.3 mm on MRIs and 27.3 mm in anatomic specimens. We found statistically significant difference of the STN width and length between individuals <60 and ≥60 years old. Conclusion. The identification of the STN limits was easier in anatomic specimens than on MRIs and easier on T2 compared to T1-weighted MRIs sections. STN dimensions appear slightly smaller on MRIs. Younger people have wider and longer STN.

摘要

目的。我们的目的是开展一项以临床为导向的综合性研究,重点关注人类丘脑底核(STN)的详细解剖结构及其靶点。方法。在影像学研究中,我们使用了26例神经外科患者的脑磁共振成像(MRI);在解剖学研究中,我们使用了来自18例尸体供体正常大脑的32个大脑半球。我们测量并分析了STN的尺寸(基于其立体定向坐标)。结果。在立体定向层面Z = -4时,MRI上STN的长度为7.7毫米,解剖标本中为8.1毫米。其宽度在MRI上为6毫米,解剖标本中为6.3毫米。STN在3.2个横向MRI切片上平均可见,其最大尺寸为8.5毫米。MRI上的连合间距离为26.3毫米,解剖标本中为27.3毫米。我们发现年龄<60岁和≥60岁的个体之间,STN的宽度和长度存在统计学上的显著差异。结论。在解剖标本中识别STN的边界比在MRI上更容易,并且在T2加权MRI切片上比T1加权MRI切片上更容易。MRI上STN的尺寸似乎略小。年轻人的STN更宽更长。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/096b1b347d08/ARI2013-319710.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/a2870ba27698/ARI2013-319710.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/75f2134185a1/ARI2013-319710.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/096b1b347d08/ARI2013-319710.003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/a2870ba27698/ARI2013-319710.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/75f2134185a1/ARI2013-319710.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a8c/3876692/096b1b347d08/ARI2013-319710.003.jpg

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