Mavridis Ioannis, Boviatsis Efstathios, Anagnostopoulou Sophia
Department of Anatomy, University of Athens School of Medicine, Mikras Assias str. 75, Goudi, 11527, Athens, Greece.
Surg Radiol Anat. 2011 Jul;33(5):405-14. doi: 10.1007/s00276-010-0766-6. Epub 2011 Jan 4.
The human nucleus accumbens (NA), which belongs to the basal ganglia of the brain, is the main part of the ventral striatum. The purpose of our clinically oriented anatomical-radiologic study was to provide anatomical and imaging data of the human NA, primarily useful to neurosurgeons.
For our imaging study, we used cerebral magnetic resonance images (MRIs) from 26 neurosurgical patients (52 NAs). The material for our anatomic study consisted of 32 cerebral hemispheres (32 NAs) from 18 normal human brains which we have in our department (Department of Anatomy) from cadaver donors. We measured and analyzed the dimensions of the NA at specific clinically important transverse, coronal and sagittal levels.
The human NA suffers from age-related but no side- or sex-related morphometric changes. In surgically important stereotactic levels this nucleus is easily identifiable on MRIs.
We present an anatomic guide of the NA from carefully measured data of our extensive and combined study and we hope that our work will be really helpful to neuroscientists interested in the NA.
伏隔核(NA)属于脑基底神经节,是腹侧纹状体的主要部分。我们这项以临床为导向的解剖学 - 放射学研究的目的是提供人类NA的解剖学和影像学数据,主要供神经外科医生使用。
在影像学研究中,我们使用了26例神经外科患者(52个NA)的脑磁共振成像(MRI)。解剖学研究材料包括我们解剖学系从尸体捐赠者处获得的18个正常人类大脑的32个脑半球(32个NA)。我们在特定的具有临床重要意义的横断、冠状和矢状层面测量并分析了NA的尺寸。
人类NA存在与年龄相关的形态学变化,但不存在与左右侧或性别相关的形态学变化。在具有手术重要性的立体定向层面上,该核在MRI上易于识别。
我们根据广泛综合研究的精确测量数据,展示了NA的解剖学指南,希望我们的工作能真正帮助对NA感兴趣的神经科学家。