Majumder Poulami, Nair Vineet, Mukherjee Malancha, Ghosh Sujoy, Dey Subrata Kumar
Department of Biotechnology, Centre for Genetic Studies, School of Biotechnology and Biological Sciences, West Bengal University of Technology, BF-142, Sector I, Salt Lake City, Kolkata, West Bengal 700064, India.
Department of Periodontics & Oral Implantology, Dr. R. Ahmed Dental College & Hospital, Kolkata, West Bengal 700014, India.
Case Rep Dent. 2013;2013:432864. doi: 10.1155/2013/432864. Epub 2013 Dec 14.
Hereditary gingival fibromatosis (HGF) is a rare condition which is marked by enlargement of gingival tissue that covers teeth to various extents leading to aesthetic disfigurement. This study presents a case of a 28-year-old female patient and 18-year-old male who belong to the same family suffering from HGF with chief complaint of overgrowing swelling gingiva. The presence of enlarged gingiva with the same eruption was found in their other family members with no concomitant drug or medical history, and the occurrence of HGF has been found in one generation of this family which may indicate the autosomal recessive inheritance pattern of HGF. Hereditary gingival fibromatosis is an idiopathic condition as its etiology is unknown and it was found to recur in some cases even after surgical treatment. Both patients underwent thorough oral prophylaxis and later surgical therapy to correct the deformity.
遗传性牙龈纤维瘤病(HGF)是一种罕见病症,其特征是牙龈组织不同程度地覆盖牙齿而肿大,导致美观受损。本研究报告了一例28岁女性患者和一名18岁男性患者,他们来自同一个患有HGF的家庭,主要症状为牙龈过度生长肿胀。在他们其他没有相关药物或病史的家庭成员中,也发现了相同萌牙期牙龈肿大的情况,并且在这个家族的一代中出现了HGF,这可能表明HGF为常染色体隐性遗传模式。遗传性牙龈纤维瘤病是一种特发性病症,因为其病因不明,并且发现有些病例即使在手术治疗后仍会复发。两名患者均接受了全面的口腔预防措施,随后进行了手术治疗以矫正畸形。