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强迫症的两种障碍:强迫观念,作为思维抑制的问题;强迫行为,作为行为执行障碍。

Two types of impairments in OCD: obsessions, as problems of thought suppression; compulsions, as behavioral-executive impairment.

机构信息

Nyírő Gyula Hospital, II Psychiatric Department, Lehel út 59, 1135 Budapest, Hungary.

Nyírő Gyula Hospital, II Psychiatric Department, Lehel út 59, 1135 Budapest, Hungary.

出版信息

Psychiatry Res. 2014 Mar 30;215(3):651-8. doi: 10.1016/j.psychres.2013.11.014. Epub 2013 Nov 20.

Abstract

Impairments in executive functioning have been identified as an underlying cause of Obsessive-Compulsive Disorder (OCD). Obsessive patients attempt to suppress certain unwanted thoughts through a mechanism that Wegner referred to as 'chronic thought suppression', whereas compulsive patients are unable to inhibit their rituals. We tested 51 OCD patients using the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), the White Bear Suppression Inventory (WBSI) and the Dysexecutive Questionnaire (DEX). Executive functions were tested using a cognitive test battery. We found that the total WBSI score was correlated with the Y-BOCS obsessive score but not with the Y-BOCS compulsive score. A stronger correlation was observed between the Y-BOCS obsessive score and the 'unwanted intrusive thoughts' factor based on Blumberg's 3-factor model of the WBSI. The total WBSI score was not correlated with the cognitive test results. The DEX score was significantly correlated with the Y-BOCS compulsive score; however, no correlation was found between the DEX score and the Y-BOCS obsessive score. A stronger correlation was observed between the Y-BOCS compulsive score and the 'inhibition' component of the DEX score, as defined by Burgess's 5-factor model. The DEX scores were correlated with cognitive test results measuring attention, cognitive flexibility and inhibitory processes. We conclude that obsessions indicate a failure of cognitive inhibition but do not involve significant impairment of executive functions, whereas compulsions indicate ineffective behavior inhibition and impaired executive functions.

摘要

执行功能障碍已被确定为强迫症(OCD)的潜在原因。强迫患者试图通过威格纳(Wegner)所谓的“慢性思维抑制”机制来抑制某些不必要的想法,而强迫患者则无法抑制其仪式。我们使用耶鲁-布朗强迫量表(Y-BOCS)、白熊抑制量表(WBSI)和执行功能障碍问卷(DEX)测试了 51 名 OCD 患者。使用认知测试组合测试执行功能。我们发现,总 WBSI 评分与 Y-BOCS 强迫评分相关,但与 Y-BOCS 强迫评分无关。在基于 Blumberg 的 WBSI 的三因素模型的基础上,WBSI 的“不想要的侵入性思维”因子与 Y-BOCS 强迫评分之间观察到更强的相关性。总 WBSI 评分与认知测试结果无关。DEX 评分与 Y-BOCS 强迫评分显著相关;然而,DEX 评分与 Y-BOCS 强迫评分之间没有相关性。在 Burgess 的五因素模型中,DEX 评分与“抑制”成分与 Y-BOCS 强迫评分之间观察到更强的相关性。DEX 评分与测量注意力、认知灵活性和抑制过程的认知测试结果相关。我们得出结论,强迫症表明认知抑制失败,但不涉及执行功能的重大损害,而强迫症则表明行为抑制无效和执行功能受损。

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