神经性厌食症患者的肠道微真核生物：一例报告
Gut microeukaryotes during anorexia nervosa: a case report.
作者信息
Gouba Nina, Raoult Didier, Drancourt Michel
机构信息
Aix Marseille Université, URMITE, UMR63, CNRS 7278, IRD 198, Inserm 1095, Marseille 13005, France.
出版信息
BMC Res Notes. 2014 Jan 13;7:33. doi: 10.1186/1756-0500-7-33.
Abstract
BACKGROUND
Few studies have focused on eukaryote community in the human gut. Here, the diversity of microeukaryotes in the gut microbiota of an anorexic patient was investigated using molecular and culture approaches.
CASE PRESENTATION
A 21-year-old Caucasian woman was admitted in an intensive care unit for severe malnutrition in anorexia nervosa. One stool specimen was collected from the anorexic patient, culture and polymerase chain reaction-based explorations yielded a restricted diversity of fungi but four microeukaryotes Tetratrichomonas sp., Aspergillus ruber, Penicillium solitum and Cladosporium bruhnei previously undescribed in the human gut.
CONCLUSIONS
Establishing microeukaryote repertoire in gut microbiota contributes to the understanding of its role in human health.
摘要
背景
很少有研究聚焦于人类肠道中的真核生物群落。在此，采用分子和培养方法对一名厌食症患者肠道微生物群中的微真核生物多样性进行了研究。
病例介绍
一名21岁的白种女性因神经性厌食症导致的严重营养不良入住重症监护病房。从该厌食症患者采集了一份粪便标本，培养和基于聚合酶链反应的探索发现真菌多样性有限，但发现了四种此前未在人类肠道中描述过的微真核生物，即四毛滴虫属、红曲霉、孤生青霉和布鲁内枝孢霉。
结论
确定肠道微生物群中的微真核生物种类有助于理解其在人类健康中的作用。
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