Cullen Doris, Keithly Lois, Kane Kevin, Land Thomas, Paskowsky Mark, Chen Lili, Hayes Rashelle, Li Wenjun
Bureau of Community Health and Prevention, Massachusetts Department of Public Health, Boston, Massachusetts, USA.
Health Statistics and Geography Lab, Division of Preventive and Behavioral Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA.
Tob Control. 2015 May;24(3):256-62. doi: 10.1136/tobaccocontrol-2013-051225. Epub 2014 Jan 13.
Sales of smokeless tobacco products have increased in the USA. More than one in eight males in the 12th grade are current users of smokeless tobacco. Surveillance data examining nicotine levels of smokeless tobacco subsequent to 2006 have not been reported in the literature.
Data on nicotine levels and design features (eg, pH, moisture content, leaf cut and flavour) of smokeless tobacco products sold in Massachusetts were obtained from manufacturers between 2003 and 2012. Design features, levels and temporal trends in unionised (free) nicotine and nicotine content of smokeless tobacco products were analysed overall and by manufacturer and product type.
The annual total number of moist snuff products increased from 99 in 2003 to 127 in 2012. The annual total number of reported snus products increased from 4 in 2003 to the highest level of 62 in 2011, before decreasing to 26 in 2012. Overall, mean unionised (free) nicotine remained relatively stable (β=0.018 (95% CI -0.014 to 0.050) mg/g dry weight/year) from 2003 to 2012. However, both levels and temporal trends of mean free nicotine varied significantly among manufacturers (p<0.001). Since 2003, the free nicotine content of snus has increased at an overall rate of 0.192 (95% CI 0.138 to 0.246) mg/g dry weight/year, but varied by manufacturer (p<0.001).
The number of smokeless tobacco products increased in the Massachusetts market. Further, mean unionised (free) nicotine levels in smokeless tobacco products of several manufacturers continued to rise despite decreasing levels from other manufacturers. The current success in tobacco control is very likely undermined without government surveillance, regulation and widespread public disclosure of nicotine levels in these products.
美国无烟烟草产品的销量有所增加。十二年级的男性中,超过八分之一是无烟烟草的当前使用者。2006年之后有关无烟烟草尼古丁水平的监测数据在文献中尚未见报道。
2003年至2012年期间从制造商处获取了在马萨诸塞州销售的无烟烟草产品的尼古丁水平和设计特征(如pH值、水分含量、烟叶切割和口味)的数据。对无烟烟草产品的设计特征、游离(未结合)尼古丁水平和尼古丁含量的水平及时间趋势进行了总体分析,并按制造商和产品类型进行了分析。
湿鼻烟产品的年度总数从2003年的99种增加到2012年的127种。所报告的口含烟产品的年度总数从2万3年的4种增加到2011年的最高水平62种,之后在2012年降至26种。总体而言,2003年至2012年期间,平均游离(未结合)尼古丁相对稳定(β=0.018(95%CI -0.014至0.050)mg/g干重/年)。然而,制造商之间平均游离尼古丁的水平和时间趋势差异显著(p<0.001)。自2003年以来,口含烟的游离尼古丁含量总体以0.192(95%CI 0.138至0.246)mg/g干重/年的速度增加,但因制造商而异(p<0.001)。
马萨诸塞州市场上无烟烟草产品的数量增加。此外,尽管其他制造商的水平有所下降,但几家制造商的无烟烟草产品中平均游离(未结合)尼古丁水平仍在持续上升。如果没有政府监管、规范以及对这些产品尼古丁水平的广泛公开披露,当前烟草控制方面的成果很可能会受到破坏。