苏丹口腔癌的病因
Aetiology of oral cancer in the Sudan.
作者信息
Ahmed Hussain Gadelkarim
机构信息
Department of Pathology, College of Medicine, University of Hail, KSA, University of Khartoum Sudan.
出版信息
J Oral Maxillofac Res. 2013 Jul 1;4(2):e3. doi: 10.5037/jomr.2013.4203.
OBJECTIVES
To review the studied risk factors that linked to aetiology of oral cancer in the Sudan. There have been numerous reports in the increase in the incidence of oral cancer from various parts of the world. A recent trend for a rising incidence of oral cancer, with the absence of the well established risk factors, has raised concern. Although, there are inconsistent data on incidence and demographical factors, studies suggest that the physiologic response to risk factors by men and women vary in different populations.
MATERIAL AND METHODS
This review principally examines 33 publications devoted to aetiology of oral cancer in the Sudan, in addition to some risk factors that are commonly practiced in the Sudan.
RESULTS
Several studies examining risk factors for oral cancer include tobacco use (Smoked and Smokeless), alcohol consumption, occupational risk, familial risk, immune deficits, virus infection and genetic factors.
CONCLUSIONS
Toombak use and infection with high risk Human Papilloma Virus (HPV) were extensively investigated and linked to the aetiology of oral cancer in Sudan.
目的
回顾苏丹与口腔癌病因相关的已研究风险因素。世界各地均有众多关于口腔癌发病率上升的报道。近期出现了口腔癌发病率上升的趋势，且不存在已明确的风险因素，这引发了人们的关注。尽管关于发病率和人口统计学因素的数据并不一致，但研究表明，不同人群中男性和女性对风险因素的生理反应存在差异。
材料与方法
本综述主要研究了33篇关于苏丹口腔癌病因的出版物，以及苏丹一些常见的风险因素。
结果
多项关于口腔癌风险因素的研究包括烟草使用（吸烟和无烟烟草）、饮酒、职业风险、家族风险、免疫缺陷、病毒感染和遗传因素。
结论
对图姆巴克（toombak）的使用以及高危型人乳头瘤病毒（HPV）感染进行了广泛研究，并将其与苏丹口腔癌的病因联系起来。
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