Yuan Hong-E, Zhou Xing-Dong, Meng Ling-Jie, Qin Fang-Min, Zhou Guang-Xiong
Institute of Traditional Chinese Medicine and Natural Products, College of Pharmacy, Jinan University, Guangzhou 510632, China.
Zhongguo Zhong Yao Za Zhi. 2013 Oct;38(19):3304-8.
To investigate the chemical constituents from Commelina communis, fifteen compounds were separated and purified by silica gel, Sephadex LH-20, and ODS column chromatography, and semi-preparative HPLC. By analyses of NMR and MS data as well as their physical and chemical properties, the structures of these compounds were identified as chrysoeriol-7-O-beta-D-glucoside( 1), methyl gallate(2), p-coumaric acid(3), protocatechuic acid(4), caffeic acid(5), p-hydroxybenzoic acid(6), 2-phenethyl-beta-D-gly-cosidase(7) , rhaponticin(8) , (7S, 8R) -dihydrodehydrodiconiferyl alcohol-9-O-beta-D-glucoside (9), isovitexin (10) , isofurcatain (11), isorhamnetin-3-O-beta-D-glucoside(12) , quercetin-3-O-alpha-L-rhamnoside (13) , isoquercitrin (14) , and 1, 2-dihydro-6, 8-dime-thoxy-7-1-(3, 5-dimethoxy-4-hydroxyphenyl) -N1, N2-bis-[2-( 4-hydroxyphenyl) ethyl] -2, 3-naphthalene dicarboxamide (15). Compounds 2, 5-9, 11, 13 were obtained from the genus Commelina for the first time.
为研究鸭跖草的化学成分，采用硅胶柱色谱、葡聚糖凝胶LH - 20柱色谱、ODS柱色谱及半制备高效液相色谱法分离纯化得到15个化合物。通过核磁共振波谱（NMR）、质谱（MS）数据分析及理化性质鉴定，这些化合物的结构分别为芹菜素 - 7 - O - β - D - 葡萄糖苷（1）、没食子酸甲酯（2）、对香豆酸（3）、原儿茶酸（4）、咖啡酸（5）、对羟基苯甲酸（6）、2 - 苯乙基 - β - D - 糖苷酶（7）、紫菀苷（8）、（7S，8R） - 二氢脱氢二松柏醇 - 9 - O - β - D - 葡萄糖苷（9）、异荭草素（10）、异叉分药花素（11）、异鼠李素 - 3 - O - β - D - 葡萄糖苷（12）、槲皮素 - 3 - O - α - L - 鼠李糖苷（13）、异槲皮苷（14）以及1,2 - 二氢 - 六、八 - 二甲氧基 - 7 - 1 - （3,5 - 二甲氧基 - 4 - 羟基苯基） - N1，N2 - 双 - [2 - （4 - 羟基苯基）乙基] - 2,3 - 萘二甲酰胺（15）。化合物2、5 - 9、11、13为首次从鸭跖草属植物中获得。
