Nakajima Tooru, Taniwaka Kouichi, Yoshioka Takafusa, Abe Shinya, Kamei Takao, Goto Hideki
Dept. of Surgery, Kanbara Municipal Hospital.
Gan To Kagaku Ryoho. 2014 Jan;41(1):87-9.
The patient was a 56-year-old woman who had undergone the Patey operation for left breast cancer when she was 45 years old. She had complained of dyspnea and shortness of breath at the time of exercise. Bilateral accumulation of pleural effusion and pericardial fluid was observed on chest radiographs and computed tomography(CT)scans. Under the diagnosis of cardiac tamponade, the patient was treated with pericardial drainage and local chemotherapy(intra-pericardial dosage of paclitaxel 45 mg and minocycline 100 mg)with the aim of preventing the accumulation of pericardial effusion. Subsequently, the pericardial effusion continued to disappear. The patient was treated with systemic chemotherapy. At the age of 58 years, she died of breast cancer. After treatment with pericardial drainage and local chemotherapy, she did not experience pericardial reaccumulation or cardiac tamponade. Thus, the method of local chemotherapy(intra-pericardial dosage of paclitaxel 45 mg and minocycline 100 mg)was considered effective.
该患者为一名56岁女性，45岁时因左乳腺癌接受了帕蒂手术。她在运动时曾抱怨呼吸困难和气促。胸部X线片和计算机断层扫描（CT）显示双侧胸腔积液和心包积液。在诊断为心脏压塞后，对患者进行了心包引流和局部化疗（心包内注射紫杉醇45mg和米诺环素100mg），目的是防止心包积液的积聚。随后，心包积液持续消失。患者接受了全身化疗。58岁时，她死于乳腺癌。在心包引流和局部化疗后，她没有出现心包积液再积聚或心脏压塞。因此，局部化疗方法（心包内注射紫杉醇45mg和米诺环素100mg）被认为是有效的。
