Hosogi Hisahiro, Yoshimura Fumihiro, Yamaura Tadayoshi, Satoh Seiji, Uyama Ichiro, Kanaya Seiichiro
Department of Surgery, Osaka Red Cross Hospital, 5-30, Fudegasaki-cho, Tennouji-ku, Osaka, 543-8555, Japan,
Langenbecks Arch Surg. 2014 Apr;399(4):517-23. doi: 10.1007/s00423-014-1163-0. Epub 2014 Jan 15.
The incidence of adenocarcinoma of the esophagogastric junction is increasing, but laparoscopic proximal gastrectomy is not widely accepted due to the absence of a standardized technique of reconstruction. This report describes a novel technique of esophagogastric tube reconstruction in laparoscopic proximal gastrectomy for Siewert type II tumors.
Laparoscopic proximal gastrectomy, sometimes with transhiatal distal esophagectomy, was performed. After a perigastric, suprapancreatic, and lower thoracic paraesophageal lymphadenectomy, a gastric tube of 35-mm width was prepared. An esophagogastric tube anastomosis with pseudo-fornix was made with a no-knife linear stapler to prevent postoperative reflux esophagitis.
Fifteen patients with Siewert type II tumors underwent this operation. They included six patients with early-stage cancer, six at high risk for transhiatal total gastrectomy due to several comorbidities, and three who needed palliative tumor resection. The mean operation time was 315 min. One postoperative anastomotic leak was treated conservatively, and three anastomotic stenoses were resolved with endoscopic balloon dilatation. Postoperative 1-year follow-up endoscopy revealed four cases of reflux esophagitis that were well controlled by medication.
This new technique of reconstruction was feasible. With the advantage of a gastric tube, a tension-free anastomosis was possible even for bulky tumors that needed lower esophagectomy. Although long-term follow-up and a larger number of patients are required to evaluate long-term functional outcomes and oncological adequacy, our procedure has the potential of becoming a treatment of choice for early-stage Siewert type II tumors and/or for some selected high-risk patients who need tumor resection.
食管胃交界腺癌的发病率正在上升,但由于缺乏标准化的重建技术,腹腔镜近端胃切除术尚未被广泛接受。本报告描述了一种用于Siewert II型肿瘤的腹腔镜近端胃切除术中食管胃管重建的新技术。
实施腹腔镜近端胃切除术,有时联合经裂孔远端食管切除术。在进行胃周、胰上和胸段食管下段旁淋巴结清扫后,制备宽度为35mm的胃管。使用无刀线性吻合器进行食管胃管假穹隆吻合,以预防术后反流性食管炎。
15例Siewert II型肿瘤患者接受了该手术。其中包括6例早期癌症患者,6例因多种合并症而进行经裂孔全胃切除术风险较高的患者,以及3例需要姑息性肿瘤切除的患者。平均手术时间为315分钟。1例术后吻合口漏保守治疗,3例吻合口狭窄经内镜球囊扩张解决。术后1年随访内镜检查发现4例反流性食管炎,经药物治疗得到良好控制。
这种新的重建技术是可行的。借助胃管的优势,即使对于需要低位食管切除术的巨大肿瘤,也能实现无张力吻合。尽管需要长期随访和更多患者来评估长期功能结果和肿瘤学充分性,但我们的手术方法有可能成为早期Siewert II型肿瘤和/或某些需要肿瘤切除的选定高危患者的首选治疗方法。