• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

腹腔镜胃近端切除术治疗上三分之一胃癌的手术效果:食管胃吻合术、胃管重建和双道重建。

Surgical outcomes of laparoscopic proximal gastrectomy for upper-third gastric cancer: esophagogastrostomy, gastric tube reconstruction, and double-tract reconstruction.

机构信息

Department of Clinical Medical College, The Yangzhou School of Clinical Medicine, Dalian Medical University, Yangzhou, People's Republic of China.

Department of General Surgery, Northern Jiangsu People's Hospital, Clinical Medical School, Yangzhou University, 98 Nantong West Road, Yangzhou, 225001, People's Republic of China.

出版信息

BMC Surg. 2023 Oct 12;23(1):309. doi: 10.1186/s12893-023-02219-9.

DOI:10.1186/s12893-023-02219-9
PMID:37828530
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10571476/
Abstract

BACKGROUND

There is no consensus on the optimal reconstruction technique after proximal gastrectomy. The purpose of this study was to retrospectively compare the surgical outcomes among esophagogastrostomy (EG) anastomosis, gastric tube (GT) reconstruction and double-tract (DT) reconstruction in patients who underwent laparoscopic proximal gastrectomy (LPG) to clarify the superior reconstruction method.

METHODS

This study enrolled 164 patients who underwent LPG at the Northern Jiangsu People's Hospital in Jiangsu between January 2017 to January 2022 (EG: 51 patients; GT: 77 patients; DT: 36 patients). We compared the clinical and pathological characteristics, surgical features, postoperative complications, nutritional status, and quality of life (QOL) among the above three groups.

RESULTS

Mean operative time was longer with the DT group than the remaining two groups (p = 0.001). With regard to postoperative complications, considerable differences in the postoperative reflux symptoms (p = 0.042) and reflux esophagitis (p = 0.040) among the three groups were found. For the nutritional status, total protein, hemoglobin and albumin reduction rates in the GT group were significantly higher than the other two groups at 12 months postoperatively. In the PGSAS-45, three assessment items were better in the DT group significantly compared with the esophageal reflux subscale (p = 0.047, Cohen's d = 0.44), dissatisfaction at the meal (p = 0.009, Cohen's d = 0.58), and dissatisfaction for daily life subscale (p = 0.012, Cohen's d = 0.56).

CONCLUSIONS

DT after LPG is a valuable reconstruction technique with satisfactory surgical outcomes, especially regarding reduced reflux symptoms, improving the postoperative nutritional status and QOL.

摘要

背景

近端胃切除术后的最佳重建技术尚无共识。本研究旨在回顾性比较腹腔镜近端胃切除术后行食管胃吻合术(EG)吻合、胃管(GT)重建和双管(DT)重建的手术结果,以明确更优的重建方法。

方法

本研究纳入了 2017 年 1 月至 2022 年 1 月期间在江苏省苏北人民医院接受腹腔镜近端胃切除术的 164 例患者(EG 组 51 例;GT 组 77 例;DT 组 36 例)。我们比较了三组患者的临床和病理特征、手术特点、术后并发症、营养状况和生活质量(QOL)。

结果

DT 组的平均手术时间长于其余两组(p=0.001)。在术后反流症状(p=0.042)和反流性食管炎(p=0.040)方面,三组之间存在明显差异。在营养状况方面,GT 组术后 12 个月的总蛋白、血红蛋白和白蛋白降低率明显高于其余两组。在 PGSAS-45 中,DT 组在三个评估项目上明显优于食管反流亚量表(p=0.047,Cohen's d=0.44)、对进餐的不满(p=0.009,Cohen's d=0.58)和对日常生活的不满亚量表(p=0.012,Cohen's d=0.56)。

结论

LPG 后的 DT 是一种有价值的重建技术,具有满意的手术结果,尤其是在减轻反流症状、改善术后营养状况和 QOL 方面。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27d0/10571476/67a6048799cd/12893_2023_2219_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27d0/10571476/67a6048799cd/12893_2023_2219_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27d0/10571476/67a6048799cd/12893_2023_2219_Fig1_HTML.jpg

相似文献

1
Surgical outcomes of laparoscopic proximal gastrectomy for upper-third gastric cancer: esophagogastrostomy, gastric tube reconstruction, and double-tract reconstruction.腹腔镜胃近端切除术治疗上三分之一胃癌的手术效果:食管胃吻合术、胃管重建和双道重建。
BMC Surg. 2023 Oct 12;23(1):309. doi: 10.1186/s12893-023-02219-9.
2
[Comparison of quality-of-life after proximal gastrectomy with double tract reconstruction versus gastric tube reconstruction in patients with proximal gastric cancer].近端胃癌患者近端胃切除术后双通路重建与胃管重建的生活质量比较
Zhonghua Wei Chang Wai Ke Za Zhi. 2023 Dec 25;26(12):1162-1170. doi: 10.3760/cma.j.cn441530-20230204-00026.
3
[Short-term outcomes and long-term quality of life after undergoing radical proximal gastrectomy with esophageal gastric tube anastomosis and total gastrectomy with Roux-en-Y anastomosis for Siewert type II and III adenocarcinoma of the esophagogastric junction: A propensity score matching analysis].[食管胃交界部Siewert II型和III型腺癌行近端胃根治性切除食管胃管吻合术及全胃切除Roux-en-Y吻合术后的短期结局和长期生活质量:一项倾向评分匹配分析]
Zhonghua Wei Chang Wai Ke Za Zhi. 2023 Feb 25;26(2):181-190. doi: 10.3760/cma.j.cn441530-20220728-00330.
4
Double tract reconstruction versus double flap technique: short-term clinical outcomes after laparoscopic proximal gastrectomy for early gastric cancer.双管重建与双瓣技术:腹腔镜近端胃切除治疗早期胃癌的短期临床结果。
Surg Endosc. 2022 Jul;36(7):5243-5256. doi: 10.1007/s00464-021-08902-3. Epub 2022 Jan 8.
5
Superiority of laparoscopic proximal gastrectomy with hand-sewn esophagogastrostomy over total gastrectomy in improving postoperative body weight loss and quality of life.腹腔镜近端胃切除术加手工吻合食管胃吻合术优于全胃切除术,可改善术后体重减轻和生活质量。
Surg Endosc. 2017 Sep;31(9):3664-3672. doi: 10.1007/s00464-016-5403-y. Epub 2017 Jan 11.
6
[Efficacy of laparoscopic proximal gastrectomy with double-tract reconstruction versus laparoscopic total gastrectomy with Roux-en-Y reconstruction for early upper gastric cancer].腹腔镜近端胃切除术双通路重建与腹腔镜全胃切除术Roux-en-Y重建治疗早期胃上部癌的疗效比较
Zhonghua Wei Chang Wai Ke Za Zhi. 2022 May 25;25(5):412-420. doi: 10.3760/cma.j.cn441530-20211118-00466.
7
Feasibility and quality of life assessment of laparoscopic proximal gastrectomy using double-tract reconstruction.双管重建腹腔镜近端胃切除术的可行性和生活质量评估。
Langenbecks Arch Surg. 2021 Mar;406(2):479-489. doi: 10.1007/s00423-020-02076-7. Epub 2021 Jan 15.
8
Clinical outcomes of gastric tube reconstruction following laparoscopic proximal gastrectomy for early gastric cancer in the upper third of the stomach: experience with 100 consecutive cases.胃上部癌行腹腔镜近端胃大部切除术后胃管重建的临床效果:100 例连续病例经验。
Langenbecks Arch Surg. 2021 May;406(3):659-666. doi: 10.1007/s00423-021-02132-w. Epub 2021 Feb 21.
9
Safety and short-term outcomes of a modified valvuloplastic esophagogastrostomy versus gastric tube anastomosis after laparoscopy-assisted proximal gastrectomy: a retrospective cohort study.腹腔镜辅助近端胃切除术后改良贲门成形术与胃管吻合术的安全性和短期结果:回顾性队列研究。
Surg Endosc. 2024 Mar;38(3):1523-1532. doi: 10.1007/s00464-023-10663-0. Epub 2024 Jan 25.
10
Comparison of nutrition and quality of life of esophagogastrostomy and the double-tract reconstruction after laparoscopic proximal gastrectomy.腹腔镜近端胃切除术后食管胃吻合与双通道重建的营养和生活质量比较。
Medicine (Baltimore). 2021 Apr 16;100(15):e25453. doi: 10.1097/MD.0000000000025453.

引用本文的文献

1
Comparison of postoperative reflux esophagitis in different digestive tract reconstruction methods after proximal gastrectomy for proximal gastric cancer patients: a network meta-analysis and systematic review.近端胃癌患者近端胃切除术后不同消化道重建方法的术后反流性食管炎比较:一项网状Meta分析和系统评价
Updates Surg. 2025 Aug 6. doi: 10.1007/s13304-025-02300-3.
2
Safety and short‑term outcomes of a modified tubular esophagogastrostomy versus double tract reconstruction after proximal gastrectomy: a propensity score matching analysis.近端胃切除术后改良管状食管胃吻合术与双通道重建术的安全性及短期结局:一项倾向评分匹配分析
BMC Cancer. 2025 May 21;25(1):908. doi: 10.1186/s12885-025-14284-9.
3

本文引用的文献

1
Impact of Tumor Location on the Quality of Life of Patients Undergoing Total or Proximal Gastrectomy.肿瘤位置对接受全胃或近端胃切除术患者生活质量的影响。
J Gastric Cancer. 2022 Jul;22(3):235-247. doi: 10.5230/jgc.2022.22.e23.
2
Effects of Proximal Gastrectomy and Various Clinical Factors on Postoperative Quality of Life for Upper-third Gastric Cancer Assessed using the Postgastrectomy Syndrome Assessment Scale-45 (PGSAS-45): A PGSAS NEXT Study.近端胃切除术及各种临床因素对上三分之一胃癌术后生活质量的影响:基于胃切除术后综合征评估量表-45(PGSAS-45)的评估:PGSAS NEXT 研究。
Ann Surg Oncol. 2022 Jun;29(6):3899-3908. doi: 10.1245/s10434-021-11136-1. Epub 2022 Jan 5.
3
Updated Review of Proximal Gastrectomy for Gastric Cancer or Cancer of the Gastroesophageal Junction.
胃癌或胃食管交界癌近端胃切除术的最新综述
J Gastric Cancer. 2025 Jan;25(1):228-246. doi: 10.5230/jgc.2025.25.e12.
4
The comparison of post-proximal gastrectomy digestive tract reconstruction methods.近端胃切除术后消化道重建方法的比较
BMC Surg. 2025 Jan 3;25(1):1. doi: 10.1186/s12893-024-02748-x.
5
The Safety and Anti-Reflex Effect of Robotic Double-Tract Reconstruction After Proximal Gastrectomy for Gastric Cancer.机器人辅助近端胃癌根治术后双通路重建的安全性及抗反流效果
Asian J Endosc Surg. 2025 Jan-Dec;18(1):e70001. doi: 10.1111/ases.70001.
6
Comparison of proximal gastrectomy with tubular esophagogastric anastomosis and total gastrectomy with Roux-en-Y reconstruction in the treatment of adenocarcinoma of the esophagogastric junction of Siewert type II/III at stage II.比较近端胃切除术伴管状食管胃吻合术与全胃切除术伴 Roux-en-Y 重建治疗 Siewert Ⅱ/Ⅲ型食管胃结合部腺癌Ⅱ期。
BMC Surg. 2024 Nov 30;24(1):382. doi: 10.1186/s12893-024-02685-9.
7
Exploratory study on the impact of intraesophageal pressure on quality of life in patients following total gastrectomy: a retrospective cohort study.食管内压对全胃切除术后患者生活质量影响的探索性研究:一项回顾性队列研究。
BMC Surg. 2024 Jul 27;24(1):217. doi: 10.1186/s12893-024-02504-1.
8
Predicting the prognosis of operable gastric cancer patients by dynamic changes in platelets before and after surgery: a retrospective cohort study.通过手术前后血小板的动态变化预测可手术胃癌患者的预后:一项回顾性队列研究
J Cancer Res Clin Oncol. 2023 Nov;149(17):15479-15487. doi: 10.1007/s00432-023-05334-5. Epub 2023 Aug 29.
Various Kinds of Functional Digestive Tract Reconstruction Methods After Proximal Gastrectomy.
近端胃切除术后的各种功能性消化道重建方法。
Front Oncol. 2021 Aug 3;11:685717. doi: 10.3389/fonc.2021.685717. eCollection 2021.
4
Proximal gastrectomy with gastric tube reconstruction or jejunal interposition reconstruction in upper-third gastric cancer: which offers better short-term surgical outcomes?近端胃切除术联合胃管重建或空肠间置术重建在上三分之一胃癌中的应用:哪一种能提供更好的短期手术效果?
BMC Surg. 2021 Jul 5;21(1):249. doi: 10.1186/s12893-021-01239-7.
5
Comparison of effects of six main gastrectomy procedures on patients' quality of life assessed by Postgastrectomy Syndrome Assessment Scale-45.通过胃切除术后综合征评估量表-45评估六种主要胃切除手术对患者生活质量的影响比较。
World J Gastrointest Surg. 2021 May 27;13(5):461-475. doi: 10.4240/wjgs.v13.i5.461.
6
Comparison of nutrition and quality of life of esophagogastrostomy and the double-tract reconstruction after laparoscopic proximal gastrectomy.腹腔镜近端胃切除术后食管胃吻合与双通道重建的营养和生活质量比较。
Medicine (Baltimore). 2021 Apr 16;100(15):e25453. doi: 10.1097/MD.0000000000025453.
7
Clinical outcomes of gastric tube reconstruction following laparoscopic proximal gastrectomy for early gastric cancer in the upper third of the stomach: experience with 100 consecutive cases.胃上部癌行腹腔镜近端胃大部切除术后胃管重建的临床效果:100 例连续病例经验。
Langenbecks Arch Surg. 2021 May;406(3):659-666. doi: 10.1007/s00423-021-02132-w. Epub 2021 Feb 21.
8
Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries.《全球癌症统计数据 2020:全球 185 个国家和地区 36 种癌症的发病率和死亡率估计》。
CA Cancer J Clin. 2021 May;71(3):209-249. doi: 10.3322/caac.21660. Epub 2021 Feb 4.
9
Feasibility and quality of life assessment of laparoscopic proximal gastrectomy using double-tract reconstruction.双管重建腹腔镜近端胃切除术的可行性和生活质量评估。
Langenbecks Arch Surg. 2021 Mar;406(2):479-489. doi: 10.1007/s00423-020-02076-7. Epub 2021 Jan 15.
10
Double Tract Reconstruction Reduces Reflux Esophagitis and Improves Quality of Life after Radical Proximal Gastrectomy for Patients with Upper Gastric or Esophagogastric Adenocarcinoma.双管重建术减少了胃上部癌或食管胃结合部腺癌根治性近端胃切除术后的反流性食管炎,并改善了患者的生活质量。
Cancer Res Treat. 2021 Jul;53(3):784-794. doi: 10.4143/crt.2020.1064. Epub 2020 Dec 29.