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严重的全身感染掩盖了潜在的儿童白血病。

Severe systemic infection masking underlying childhood leukemia.

作者信息

Rajendran Aruna, Trehan Amita, Ahluwalia Jasmina, Marwaha Ram Kumar

机构信息

Pediatric Hematology Oncology unit, Department of Pediatrics, Advanced Pediatrics Centre, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012 India.

Department of Hematology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.

出版信息

Indian J Hematol Blood Transfus. 2013 Sep;29(3):167-70. doi: 10.1007/s12288-012-0166-7. Epub 2012 Jul 25.

DOI:10.1007/s12288-012-0166-7
PMID:24426366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3710556/
Abstract

Severe childhood infections can occasionally be accompanied by bone marrow suppression. It is unusual for infection induced marrow aplasia to evolve into acute leukemia. We share our experience in managing four children with severe sepsis and pancytopenia which in due course evolved into acute leukemia. This report emphasizes that sepsis related pancytopenia can be a harbinger of evolving hematopoietic disorders.

摘要

严重的儿童感染偶尔会伴有骨髓抑制。感染所致的骨髓再生障碍演变为急性白血病的情况并不常见。我们分享了对四名患有严重脓毒症和全血细胞减少症儿童的治疗经验，这些儿童在病程中均演变为急性白血病。本报告强调，脓毒症相关的全血细胞减少症可能是造血系统疾病演变的先兆。

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