Jain Vinod, Misra Samir, Ahmad Faraz, Rahul Kumar, Singh Amit
Department of Surgery, C. S. M. Medical University, B-41, Mahanagar Extension, Lucknow, UP India 226006.
Indian J Surg. 2013 Jun;75(Suppl 1):286-9. doi: 10.1007/s12262-012-0672-8. Epub 2012 Jul 7.
Mucosa-associated lymphoid tissue lymphomas (MALT lymphoma) are well known, but colonic MALT lymphomas are extremely rare. We report the first case of mucosa-associated lymphoid tissue (MALT) lymphoma in the cecum from India presenting as acute intestinal obstruction with mass in right iliac fossa showing diffuse thickening of ascending colon and caecum with obliterated lumen along with nodular mass on CECT scan of abdomen. On video colonoscopy, circumferential ulcerated growth was seen at cecum, and the rest of the colon was normal. Multiple biopsies from growth suggested malignancy. Right hemicolectomy was performed. The histopathology of resected specimen demonstrated low-grade B-cell MALT lymphoma of the cecum, and the depth of invasion was up to the muscular layer. This was confirmed by immunohistochemistry.
黏膜相关淋巴组织淋巴瘤(MALT淋巴瘤)广为人知,但结肠MALT淋巴瘤极为罕见。我们报告了印度首例盲肠黏膜相关淋巴组织(MALT)淋巴瘤,表现为急性肠梗阻,右下腹有肿块,腹部CT扫描显示升结肠和盲肠弥漫性增厚,管腔闭塞,同时有结节状肿块。在电子结肠镜检查中,可见盲肠有环形溃疡性肿物,其余结肠正常。肿物的多次活检提示为恶性肿瘤。遂行右半结肠切除术。切除标本的组织病理学检查显示为盲肠低度B细胞MALT淋巴瘤,浸润深度达肌层。免疫组化证实了这一诊断。