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甲状腺手术的临床病理特征及并发症:单中心经验

Clinicopathological features and complications of thyroid operations: a single centre experience.

作者信息

Gupta Sumit, Vasu Reddy C, Chettri Shyam Thapa, Karki Smriti

机构信息

Department of Otolryngology & Head and Neck Surgery, BP Koirala Institute of Health Sciences, Dharan, Nepal.

Department of Surgical Oncology, Kidwai Memorial Institute of Oncology, Bangalore, India.

出版信息

Indian J Otolaryngol Head Neck Surg. 2013 Apr;65(2):140-5. doi: 10.1007/s12070-012-0609-3. Epub 2012 Dec 22.

DOI:10.1007/s12070-012-0609-3
PMID:24427554
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3649034/
Abstract

Thyroid surgery evolution is important with a lots of hurdles faced by many surgeons to reach the present stage. The complications from the olden days reduced with improvement in understanding the disease process, development of antibiotics, anaesthesia and now restricted mainly to hypoparathyroidism and recurrent laryngeal nerve injuries. A retrospective analysis of thyroid surgeries performed at BP Koirala Institute of Health Sciences centre from 2007 to 2011 Clinicopathological features and complications were analyzed. Among 203 patients who underwent surgery for thyroid operations, 53 were malignant and 150 were benign cases. Hemithyroidectomy was the most common procedure performed (118 cases). Papillary thyroid cancer was the most common malignant lesion and colloid goiter the most common benign lesion. Postoperative complications occurred in 12 patients-infection in two patients, bleeding requiring reexploration in one patient, hypocalcemia in 6 (5-transient and 1-permanent) and hoarseness of voice in three patients (2-temporary and 1-permanent). FNAC is an easy, cost effective, reliable investigation in experienced hands. Reoperation, primary stage of the tumor and central node dissection are associated with increased complication rates.

摘要

甲状腺手术的发展历程意义重大,众多外科医生在达到当前阶段的过程中面临诸多障碍。随着对疾病过程理解的加深、抗生素及麻醉技术的发展,过去的并发症有所减少,如今主要局限于甲状旁腺功能减退和喉返神经损伤。对2007年至2011年期间在BP柯伊拉腊健康科学中心进行的甲状腺手术进行回顾性分析,分析其临床病理特征及并发症。在203例接受甲状腺手术的患者中,53例为恶性,150例为良性。甲状腺半切术是最常施行的手术(118例)。甲状腺乳头状癌是最常见的恶性病变,胶样甲状腺肿是最常见的良性病变。12例患者出现术后并发症,2例患者感染,1例患者因出血需再次探查,6例患者出现低钙血症(5例为暂时性,1例为永久性),3例患者出现声音嘶哑(2例为暂时性,1例为永久性)。在经验丰富的医生手中,细针穿刺抽吸活检(FNAC)是一种简便、经济高效且可靠的检查方法。再次手术、肿瘤的原发阶段及中央淋巴结清扫与并发症发生率增加相关。

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本文引用的文献

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Factors influencing thyroidectomy complications.影响甲状腺切除术并发症的因素。
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The Bethesda System For Reporting Thyroid Cytopathology.甲状腺细胞病理学报告的贝塞斯达系统。
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Management of the solitary thyroid nodule.孤立性甲状腺结节的管理
Oncologist. 2008 Feb;13(2):105-12. doi: 10.1634/theoncologist.2007-0212.
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The magnificent seven: a history of modern thyroid surgery.七巨头:现代甲状腺手术史
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Surgical complications after thyroid surgery performed in a cancer hospital.在一家癌症医院进行甲状腺手术后的手术并发症。
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Postoperative complications of thyroidectomy for differentiated thyroid carcinoma.分化型甲状腺癌甲状腺切除术后的并发症
Am J Otolaryngol. 2004 Jul-Aug;25(4):225-30. doi: 10.1016/j.amjoto.2004.02.001.
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Prospective study of postoperative complications after total thyroidectomy for multinodular goiters by surgeons with experience in endocrine surgery.由内分泌外科经验丰富的外科医生对多结节性甲状腺肿行全甲状腺切除术后并发症进行的前瞻性研究。
Ann Surg. 2004 Jul;240(1):18-25. doi: 10.1097/01.sla.0000129357.58265.3c.
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Total thyroidectomy for clinically benign disease of the thyroid gland.因甲状腺临床良性疾病行甲状腺全切除术。
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World J Surg. 2004 Mar;28(3):271-6. doi: 10.1007/s00268-003-6903-1. Epub 2004 Feb 17.