Plauche Virginia, Dewenter Tracy, Walvekar Rohan R
Department of Otolaryngology Head Neck Surgery, LSU Health Sciences Center, 533 Bolivar Street, Suite 566, New Orleans, LA USA.
Department of Pathology, LSU Health Sciences Center, New Orleans, LA USA.
Indian J Otolaryngol Head Neck Surg. 2013 Jul;65(Suppl 1):182-4. doi: 10.1007/s12070-011-0450-0. Epub 2012 Jan 6.
The objective of this study was to report a collision tumor of papillary and follicular carcinoma of the thyroid. Case report and review of the literature was studied. A 62 year old female presented with a thyroid mass diagnosed the year prior. Physical exam revealed a 6 × 4 cm predominantly left sided thyroid mass that was confirmed on imaging as well. Thyroid function tests were within normal limits. Ultrasound-guided fine needle aspiration suggested a follicular neoplasm. Consequently, the patient underwent a left hemi-thyroidectomy. The pathology was reported as being collision tumor with a combination of follicular and papillary carcinoma. A completion thyroidectomy was performed followed by post operative radio-iodine therapy. Collision tumors are rare involving two or more histologically distinct neoplastic morphologies separated by normal tissue in one or more organ systems. This is to our knowledge the first report of a collision tumor of the thyroid involving a follicular and papillary carcinoma.
本研究的目的是报告一例甲状腺乳头状癌和滤泡状癌的碰撞瘤。对病例报告和文献进行了研究。一名62岁女性,前一年被诊断出患有甲状腺肿块。体格检查发现一个6×4厘米、主要位于左侧的甲状腺肿块,影像学检查也证实了这一点。甲状腺功能测试在正常范围内。超声引导下细针穿刺提示为滤泡性肿瘤。因此,患者接受了左侧甲状腺叶切除术。病理报告为滤泡状癌和乳头状癌并存的碰撞瘤。随后进行了甲状腺全切术,术后进行放射性碘治疗。碰撞瘤罕见,涉及两个或更多组织学上不同的肿瘤形态,在一个或多个器官系统中被正常组织分隔。据我们所知,这是首例甲状腺滤泡状癌和乳头状癌并存的碰撞瘤报告。