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微创根治性前列腺切除术的定位相关并发症。

Positioning-related complications of minimally invasive radical prostatectomies.

机构信息

1 Department of Epidemiology, Mailman School of Public Health, Columbia University , New York, New York.

出版信息

J Endourol. 2014 Jun;28(6):660-7. doi: 10.1089/end.2013.0623. Epub 2014 Mar 31.

Abstract

BACKGROUND AND PURPOSE

Because of recent advances in minimally invasive surgical techniques, robot-assisted radical prostatectomy (RARP) has become the primary treatment option in prostate cancer. RARP, however, necessitates patients to be placed in a steep Trendelenberg position, which presents multiple opportunities for complications relating to the positioning of the patient. Our study aims to study the prevalence and demographic predictors of these positioning complications and assess their impacts on length of stay (LOS) and total cost.

PATIENTS AND METHODS

We included patients who underwent RP from 2008 to 2009 using data extracted from the Nationwide Inpatient Sample database. Positioning complications (eye, nerve, compartment syndrome/rhabdomyolysis) were identified using patient-level diagnosis and procedural International Classification of Disease, 9th edition, Clinical Modification codes. Logistic regression models assessed relationships between demographic factors and occurrence of complications and the effects of them on prolonged LOS and total inpatient cost.

RESULTS

Positioning complications occurred in 0.4% of cases with eye complications contributing the most to this frequency. Laparoscopic RP procedure (odds ratio [OR]=2.88, P<0.01) and comorbidities (OR=2.34, P<0.01) were highly associated with increased odds of positioning complication occurrence, whereas RARP procedures (OR=0.93, P>0.4) were not associated with positioning complications. Having positioning complications increased a patient's odds of having increased inpatient costs and extended LOS by almost 400% and 300%, respectively.

CONCLUSION

The steep Trendelenberg position used in RARP was not shown to be associated with patient positioning-related complications in this sample. The occurrence of positioning-related complications, however, places huge burdens on total inpatient costs and LOS.

摘要

背景与目的

由于微创外科技术的最新进展,机器人辅助根治性前列腺切除术(RARP)已成为前列腺癌的主要治疗选择。然而,RARP 需要患者处于陡峭的特伦德伦伯格体位,这为与患者体位相关的并发症提供了多种机会。我们的研究旨在研究这些定位并发症的患病率和人口统计学预测因素,并评估它们对住院时间(LOS)和总费用的影响。

患者与方法

我们从全国住院患者样本数据库中提取数据,纳入了 2008 年至 2009 年接受 RP 的患者。使用患者层面的诊断和程序国际疾病分类,第 9 版,临床修正代码来识别定位并发症(眼部、神经、间隔综合征/横纹肌溶解症)。Logistic 回归模型评估了人口统计学因素与并发症发生之间的关系,以及它们对延长 LOS 和总住院费用的影响。

结果

定位并发症的发生率为 0.4%,其中眼部并发症占比最高。腹腔镜 RP 手术(比值比[OR]=2.88,P<0.01)和合并症(OR=2.34,P<0.01)与定位并发症发生的几率增加高度相关,而 RARP 手术(OR=0.93,P>0.4)与定位并发症无关。发生定位并发症会使患者的住院费用增加近 400%,住院时间延长近 300%。

结论

在本样本中,RARP 中使用的陡峭特伦德伦伯格体位与患者定位相关并发症无关。然而,定位相关并发症的发生给总住院费用和 LOS 带来了巨大负担。

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