Molin L, Thomsen K, Volden G, Aronsson A, Hammar H, Hellbe L, Wantzin G L, Roupe G
Acta Derm Venereol. 1987;67(3):232-6.
Thirty-nine patients with mycosis fungoides in various stages or Sézary syndrome were treated with isotretinoin and 29 with etretinate as single drug therapy. Complete remission within 2 months was obtained with isotretinoin in 8 cases (21%) and partial remission in another 15 cases (38%). Etretinate induced complete remission in 5 cases (21%) and partial remission in 11 (46%). Only 1 case with Sézary syndrome went into partial remission. The first sign of remission occurred in 2 to 4 weeks. During continued treatment remissions could not always be maintained. Isotretinoin and etretinate were considered to be of equal potency in the treatment of mycosis fungoides.
39例处于不同阶段的蕈样肉芽肿或 Sézary 综合征患者接受异维甲酸单药治疗，29例患者接受依曲替酯单药治疗。异维甲酸治疗2个月内，8例（21%）获得完全缓解，另外15例（38%）获得部分缓解。依曲替酯诱导5例（21%）完全缓解，11例（46%）部分缓解。仅1例 Sézary 综合征患者获得部分缓解。缓解的首个迹象出现在2至4周。在持续治疗期间，缓解并非总能维持。异维甲酸和依曲替酯在蕈样肉芽肿治疗中被认为效力相当。
