Thomsen K, Hammar H, Molin L, Volden G
Department of Dermatology, Finsen Institute, Copenhagen, Denmark.
Acta Derm Venereol. 1989;69(6):536-8.
Sixty-nine patients with mycosis fungoides, plaque stage, were treated in an open study with photochemotherapy (PUVA) or the combination of oral retinoids and PUVA (RePUVA). The response rate of Re-PUVA was equal to that of PUVA, with complete remission in 73% and 72%, respectively. Remissions were obtained with fewer PUVA sessions, and with a lower UVA dosage, if PUVA was combined with retinoids. A lower UVA dosage was needed if treatment was given four times weekly in stead of twice weekly. The duration of the remissions tended to be prolonged if retinoids were given as maintenance therapy.
69例斑块期蕈样肉芽肿患者在一项开放性研究中接受了光化学疗法（PUVA）或口服维甲酸与PUVA联合疗法（RePUVA）治疗。RePUVA的缓解率与PUVA相当，完全缓解率分别为73%和72%。如果PUVA与维甲酸联合使用，达到缓解所需的PUVA治疗次数更少，UVA剂量更低。如果每周治疗4次而非每周2次，则所需的UVA剂量更低。如果将维甲酸作为维持疗法，缓解期往往会延长。
